SCHEMBL502558

SCHEMBL502558

Nc1ccc(S(=O)(=O)c2ccccc2Oc2ccccc2)c(Oc2ccccc2)c1N

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.40
CASP1 P29466 1/20 0.39
ADORA2A P29274 1/20 0.38
CA1 P00915 2/20 0.37
CA2 P00918 2/20 0.37
CA12 O43570 1/20 0.37
CA7 P43166 1/20 0.37
CA13 Q8N1Q1 1/20 0.37
HTR6 P50406 2/20 0.36
CTNNB1 P35222 1/20 0.36
NAMPT P43490 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
HTT P42858 1/20 0.35
KMT2A Q03164 2/20 0.35
SOS1 Q07889 1/20 0.35
CA9 Q16790 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30618213 0.91 CA1 (0.42) GAAADORA2ACA1CA2CA12
SCHEMBL3272221 0.91 CA1 (0.42) GAAADORA2ACA1CA2CA12
SCHEMBL1662788 0.84 HTR6 (0.50) GAACA1CA2CA12CA7
SCHEMBL502864 0.81 CASP1 (0.50) GAACASP1CA1CA2HTR6
SCHEMBL146565 0.81 CASP1 (0.50) GAACASP1CA1CA2HTR6
SCHEMBL11599660 0.79 CASP1 (0.49) GAACASP1CA1CA2HTR6
Ammonia Solution, Strong SCHEMBL502557 0.79 CASP1 (0.49) GAACASP1CA1CA2HTR6
SCHEMBL10411384 0.78 LMNA (0.43) GAACASP1CA1CA2CA12
SCHEMBL8772881 0.77 GAA (0.53) GAACA1CA2CA12CA7
SCHEMBL461322 0.77 GAA (0.53) GAACA1CA2CA12CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5455115-A Post-cure method for polyimide oligomers THE BOEING COMPANY (US) 1995-10-03 US claimed
US-5344894-A Polyimides for composites that are tough, solvent resistant and heat resistant THE BOEING COMPANY (US) 1994-09-06 US claimed
US-5175234-A From diamine endcapped with a monoanhydride and dianhydride; solvent, heat resistance, toughness THE BOEING COMPANY (US) 1992-12-29 US claimed
US-5011905-A Having mono- and difunctional crosslinking end caps; tough, heat and solvent resistant prepregs THE BOEING COMPANY (US) 1991-04-30 US claimed
EP-0405128-A2 Polyimide oligomers and blends and method of curing THE BOEING COMPANY (US) 1991-01-02 EP claimed
WO-1990014374-A1 POLYIMIDE OLIGOMERS AND BLENDS AND METHOD OF CURING THE BOEING COMPANY (US) 1990-11-29 WO claimed
EP-0289695-A2 Polyimide oligomers and blends THE BOEING COMPANY (US) 1988-11-09 EP claimed
EP-2438106-B1 OLIGOMERS WITH DI-PHENYLETHYNYL ENDCAPS BOEING CO (US) 2015-03-11 EP disclosed
EP-2438106-A1 OLIGOMERS WITH DI-PHENYLETHYNYL ENDCAPS The Boeing Company (US) 2012-04-11 EP disclosed
US-8106142-B2 Polyacetylinic oligomers THE BOEING COMPANY (US) 2012-01-31 US disclosed
US-8063168-B2 Oligomers with di-phenylethynyl endcaps THE BOEING COMPANY (US) 2011-11-22 US disclosed
WO-2010141106-A1 OLIGOMERS WITH DI-PHENYLETHYNYL ENDCAPS THE BOEING COMPANY (US) 2010-12-09 WO disclosed
US-20100204412-A1 OLIGOMERS WITH DI-PHENYLETHYNYL ENDCAPS THE BOEING COMPANY 2010-08-12 US disclosed
US-4847333-A Blended polyamide oligomers THE BOEING COMPANY (US) 1989-07-11 US disclosed
EP-0317754-A2 Polymide oligomers and blends THE BOEING COMPANY (US) 1989-05-31 EP disclosed
EP-0305882-A2 Amideimide oligomers & blends THE BOEING COMPANY (US) 1989-03-08 EP disclosed
EP-0294555-A2 Polyamide oligomers THE BOEING COMPANY (US) 1988-12-14 EP disclosed
EP-0292677-A2 Blended polyamide oligomers THE BOEING COMPANY (US) 1988-11-30 EP disclosed
EP-0289695-A2 Polyimide oligomers and blends THE BOEING COMPANY (US) 1988-11-09 EP disclosed
US-4684714-A Method for making polyimide oligomers THE BOEING COMPANY (US) 1987-08-04 US disclosed