Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 10/20 | 0.34 |
| ▸ | HTR2A | P28223 | 10/20 | 0.34 |
| ▸ | DRD3 | P35462 | 10/20 | 0.34 |
| ▸ | UGT8 | Q16880 | 1/20 | 0.34 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.33 |
| ▸ | RBP4 | P02753 | 2/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13201136 | 0.86 | TLR7 (0.39) | TLR7DRD2HTR2ADRD3RBP4 | |
| SCHEMBL13868776 | 0.86 | TLR7 (0.39) | TLR7DRD2HTR2ADRD3RBP4 | |
| SCHEMBL2960493 | 0.77 | CCR5 (0.41) | DRD2RBP4CCR5CHRNA7 | |
| SCHEMBL5016897 | 0.72 | SLC6A4 (0.47) | DRD2 | |
| SCHEMBL5023353 | 0.71 | HTR2A (0.48) | HTR2ADRD3 | |
| SCHEMBL2968839 | 0.70 | SLC9A1 (0.49) | HTR2ARBP4 | |
| SCHEMBL2960496 | 0.69 | RBP4 (0.40) | DRD2RBP4CCR5CHRNA7 | |
| SCHEMBL5023775 | 0.68 | DRD2 (0.37) | DRD2HTR2ADRD3 | |
| SCHEMBL5023889 | 0.67 | HTR2A (0.40) | HTR2ADRD3 | |
| SCHEMBL13523806 | 0.64 | SLC9A1 (0.46) | HTR2ARBP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1632483-B1 | HETEROCYCLIC SUBSTITUTED CARBONYL DERIVATIVES AND THEIR USE AS DOPAMINE D3 RECEPTOR LIGANDS | AVENTIS PHARMA INC (US) | 2008-10-29 | — | — | EP | claimed |