SCHEMBL5026736

SCHEMBL5026736

CCCCC(CC)CC(CC)c1cc(-n2nc3ccc(Cl)cc3n2)c(O)c(C(C)(C)C)c1

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31
MAPK1 P28482 1/20 0.31
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30
IDH1 O75874 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL208253 0.92 PRKCZ (0.32) ALDH1A1MAPK1
SCHEMBL6832895 0.84 ALDH1A1 (0.34) ALDH1A1MAPK1
SCHEMBL27182357 0.83 NPC1 (0.31) NPC1RAB9AIDH1
SCHEMBL28885881 0.82 GAA (0.34) ALDH1A1MAPK1
SCHEMBL208254 0.81 MMP2 (0.33) ALDH1A1MAPK1
SCHEMBL4207564 0.80 NPC1 (0.36) ALDH1A1MAPK1NPC1RAB9AIDH1
SCHEMBL11416629 0.80 NPC1 (0.38) ALDH1A1MAPK1NPC1RAB9AIDH1
SCHEMBL224452 0.80 MMP2 (0.36)
SCHEMBL20838546 0.80 PSEN1 (0.32) ALDH1A1
SCHEMBL6908032 0.78 NPC1 (0.36) ALDH1A1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1951501-A1 THERMOPLASTIC RESIN FILM AND METHOD FOR PRODUCING THEREOF FUJIFILM Corporation (JP) 2008-08-06 EP disclosed
WO-2007060962-A1 THERMOPLASTIC FILM AND METHOD FOR PRODUCING THEREOF FUJIFILM CORPORATION (JP) 2007-05-31 WO disclosed
WO-2007060964-A1 THERMOPLASTIC RESIN FILM AND METHOD FOR PRODUCING THEREOF FUJIFILM CORPORATION (JP) 2007-05-31 WO disclosed