Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.41 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.41 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.41 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8788719 | 0.92 | ALDH1A1 (0.48) | KDM4EALDH1A1KMT2AMAPTCHRM1 | |
| SCHEMBL8788853 | 0.87 | THRB (0.44) | KDM4EALDH1A1KMT2AMAPTCYP2C9 | |
| SCHEMBL6666984 | 0.81 | NPC1 (0.48) | KDM4EALDH1A1KMT2AMAPTCYP1A2 | |
| SCHEMBL10872657 | 0.79 | HSP90AA1 (0.49) | KDM4EALDH1A1KMT2AMAPTCYP1A2 | |
| SCHEMBL7996355 | 0.77 | SMN1; SMN2 (0.51) | KDM4EALDH1A1MAPTCHRM1CYP1A2 | |
| SCHEMBL5027701 | 0.77 | ADORA1 (0.35) | KDM4EKMT2AMAPT | |
| SCHEMBL11903503 | 0.77 | PDE10A (0.50) | KDM4EKMT2A | |
| SCHEMBL13908151 | 0.76 | KDM4E (0.47) | KDM4EALDH1A1KMT2AMAPTCHRM1 | |
| SCHEMBL8906504 | 0.76 | L3MBTL1 (0.54) | KDM4EALDH1A1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL14856866 | 0.76 | FABP6 (0.48) | ALDH1A1KMT2AMAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991013063-A1 | NEW BENZIMIDAZOLE DERIVATIVES, METHOD FOR PREPARING THEM AND THEIR PHARMACEUTICAL USE | SCHERING AKTIENGESELLSCHAFT BERLIN UND BERGKAMEN (DE) | 1991-09-05 | — | — | WO | disclosed |