SCHEMBL5028244

SCHEMBL5028244

c1ccc(-c2ccccc2-c2ccc3c(c2)c2cc(-c4ccccc4-c4ccccn4)ccc2n3-c2ccc3oc4ccc(-n5c6ccc(-c7ccccc7-c7ccccn7)cc6c6cc(-c7ccccc7-c7ccccn7)ccc65)cc4c3c2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM5 P41594 6/20 0.40
PIM1 P11309 1/20 0.35
PIM3 Q86V86 1/20 0.35
TGFBR1 P36897 2/20 0.34
MAPK14 Q16539 1/20 0.33
PRKDC P78527 1/20 0.32
FAAH O00519 1/20 0.32
CES1 P23141 1/20 0.32
TSHR P16473 2/20 0.32
HSD17B10 Q99714 2/20 0.32
MAPK1 P28482 1/20 0.32
KDR P35968 1/20 0.32
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
TP53 P04637 1/20 0.32
MAPT P10636 1/20 0.32
PKM P14618 1/20 0.32
HPGD P15428 1/20 0.32
RAB9A P51151 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16451563 0.97 GRM5 (0.38) GRM5PIM1PIM3TGFBR1MAPK14
SCHEMBL18327843 0.97 GRM5 (0.38) GRM5PIM1PIM3TGFBR1MAPK14
SCHEMBL13471340 0.97 GRM5 (0.37) GRM5PIM1PIM3TGFBR1MAPK14
SCHEMBL12114616 0.97 TGFBR1 (0.36) GRM5PIM1PIM3TGFBR1MAPK14
SCHEMBL5030309 0.97 TGFBR1 (0.36) GRM5PIM1PIM3TGFBR1MAPK14
SCHEMBL11946077 0.93 NPY5R (0.37) GRM5PIM1PIM3TGFBR1MAPK14
SCHEMBL13471317 0.93 NPC1 (0.38) GRM5PIM1PIM3TGFBR1MAPK14
SCHEMBL10123521 0.93 NPY5R (0.37) GRM5PIM1PIM3TGFBR1MAPK14
SCHEMBL13471349 0.93 TGFBR1 (0.34) GRM5PIM1PIM3TGFBR1MAPK14
SCHEMBL16451564 0.92 GRM5 (0.36) GRM5PIM1PIM3TGFBR1MAPK14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220199934-A1 LUMINESCENT FILM, ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC MATERIAL COMPOSITION AND METHOD FOR PRODUCING ORGANIC ELECTROLUMINESCENT ELEMENT UDC IRELAND LIMITED (IE) 2022-06-23 US disclosed
US-11302882-B2 Luminescent film, organic electroluminescent element, organic material composition and method for producing organic electroluminescent element MERCK PATENT GMBH (DE) 2022-04-12 US disclosed
US-20200388781-A1 LUMINESCENT FILM, ORGANIC ELECTROLUMINESCENT DEVICE, AND METHOD FOR MANUFACTURING ORGANIC ELECTROLUMINESCENT DEVICE Konica Minolta, Inc. (JP) 2020-12-10 US disclosed
US-10774261-B2 Organic electroluminescence element, illumination device, and display device Konica Minolta, Inc. (JP) 2020-09-15 US disclosed
US-20200251667-A1 MONOSUBSTITUTED DIAZABENZIMIDAZOLE CARBENE METAL COMPLEXES FOR USE IN ORGANIC LIGHT EMITTING DIODES UDC IRELAND LTD (IE) 2020-08-06 US disclosed
US-10468610-B2 Isomer-mixture metal complex composition, organic electroluminescent element, illuminator, and display device Konica Minolta, Inc. (JP) 2019-11-05 US disclosed
US-20190319210-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND COMPOSITION FOR ORGANIC MATERIALS UDC IRELAND LIMITED (IE) 2019-10-17 US disclosed
US-20190280236-A1 LUMINESCENT FILM, ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC MATERIAL COMPOSITION AND METHOD FOR PRODUCING ORGANIC ELECTROLUMINESCENT ELEMENT UDC IRELAND LIMITED (IE) 2019-09-12 US disclosed
US-10347850-B2 Organic electroluminescent element, lighting device and display device Konica Minolta, Inc. (JP) 2019-07-09 US disclosed
US-10177322-B2 Iridium complex, method for producing iridium complex, organic electroluminescent element, display device, and lighting device Konica Minolta, Inc. (JP) 2019-01-08 US disclosed
US-20130099216-A1 ORGANIC ELECTROLUMINESCENT MATERIAL, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE AND LIGHTING DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2013-04-25 US disclosed
US-20130099216-A1 ORGANIC ELECTROLUMINESCENT MATERIAL, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE AND LIGHTING DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2013-04-25 US disclosed
EP-2584019-A1 ORGANIC ELECTROLUMINESCENT MATERIAL, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE AND LIGHTING DEVICE Konica Minolta Holdings, Inc. (JP) 2013-04-24 EP disclosed
EP-2453496-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, NOVEL COMPOUND, LIGHTING DEVICE AND DISPLAY DEVICE Konica Minolta Holdings, Inc. (JP) 2012-05-16 EP disclosed
US-20120018714-A1 ORGANIC ELECTROLUMINESCENT DEVICE, DISPLAY APPARATUS, AND LIGHTING APPARATUS KONICA MINOLTA HOLDINGS, INC. (JP) 2012-01-26 US disclosed
US-20120018714-A1 ORGANIC ELECTROLUMINESCENT DEVICE, DISPLAY APPARATUS, AND LIGHTING APPARATUS KONICA MINOLTA HOLDINGS, INC. (JP) 2012-01-26 US disclosed
US-20110272687-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, AND ILLUMINATION DEVICE AND DISPLAY DEVICE EACH COMPRISING THE ELEMENT KONICA MINOLTA HOLDINGS, INC. (JP) 2011-11-10 US disclosed
US-20110272687-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, AND ILLUMINATION DEVICE AND DISPLAY DEVICE EACH COMPRISING THE ELEMENT KONICA MINOLTA HOLDINGS, INC. (JP) 2011-11-10 US disclosed
US-20110006670-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, NEW COMPOUND FOR THE SAME, DISPLAY DEVICE AND LIGHTING DEVICE USING THE SAME KONICA MINOLTA HOLDINGS, INC. (JP) 2011-01-13 US disclosed
US-20110006670-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, NEW COMPOUND FOR THE SAME, DISPLAY DEVICE AND LIGHTING DEVICE USING THE SAME KONICA MINOLTA HOLDINGS, INC. (JP) 2011-01-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10468610-B2 Isomer-mixture metal complex composition, organic electroluminescent element, illuminator, and display device EMC2, ELP1, EMC1 GRM5 820/4885PIM1 4175/4885PIM3 4213/4885
US-20200251667-A1 MONOSUBSTITUTED DIAZABENZIMIDAZOLE CARBENE METAL COMPLEXES FOR USE IN ORGANIC LIGHT EMITTING DIODES DDT, OCIAD1, OCIAD2 GRM5 1765/4885PIM1 465/4885PIM3 518/4885
US-10177322-B2 Iridium complex, method for producing iridium complex, organic electroluminescent element, display device, and lighting device EED, SNW1, AP2M1 GRM5 1749/4885PIM1 1946/4885PIM3 2511/4885
US-20110006670-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, NEW COMPOUND FOR THE SAME, DISPLAY DEVICE AND LIGHTING DEVICE USING THE SAME AOC2, AOC3, CDYL GRM5 2093/4885PIM1 3761/4885PIM3 3450/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.