Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | EDNRA | P25101 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 2/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5548058 | 0.87 | CRHBP (0.33) | SMN1; SMN2MAPTLMNATP53CYP1A2 | |
| SCHEMBL5027310 | 0.79 | CRHBP (0.37) | SMN1; SMN2MAPTLMNATP53CYP1A2 | |
| SCHEMBL11547366 | 0.71 | CYP1A2 (0.45) | SMN1; SMN2MAPTLMNATP53CYP1A2 | |
| SCHEMBL9579419 | 0.67 | MAOA (0.40) | SMN1; SMN2MAPTMEN1KMT2AEDNRA | |
| SCHEMBL14665269 | 0.67 | MAPT (0.45) | SMN1; SMN2MAPTLMNATP53CYP1A2 | |
| SCHEMBL24610064 | 0.65 | SMN1; SMN2 (0.39) | SMN1; SMN2MAPTLMNATP53CYP1A2 | |
| SCHEMBL5032009 | 0.65 | CRHBP (0.41) | SMN1; SMN2MAPTLMNAATMNPSR1 | |
| SCHEMBL10843954 | 0.65 | SMN1; SMN2 (0.65) | SMN1; SMN2MAPTLMNATP53CYP1A2 | |
| SCHEMBL3201480 | 0.65 | — | — | |
| SCHEMBL9281446 | 0.63 | ALDH1A1 (0.47) | SMN1; SMN2MAPTLMNAATMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1812370-B1 | SYNTHESIS OF CYCLOPENTENONES | FIRMENICH & CIE (CH) | 2008-06-25 | — | — | EP | disclosed |
| EP-1812370-A2 | SYNTHESIS OF CYCLOPENTENONES | FIRMENICH SA (CH) | 2007-08-01 | — | — | EP | disclosed |
| WO-2006051503-A2 | SYNTHESIS OF CYCLOPENTENONES | FIRMENICH SA (CH) | 2006-05-18 | — | — | WO | disclosed |