Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | CFTR | P13569 | 1/20 | 0.31 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5548058 | 0.85 | CRHBP (0.33) | CRHBPCRHR2LMNAMAPTPOLB | |
| SCHEMBL5027310 | 0.81 | CRHBP (0.37) | CRHBPCRHR2LMNAMAPTHTT | |
| SCHEMBL31678621 | 0.68 | ACHE (0.40) | CRHBPCRHR2LMNAMAPTHTT | |
| SCHEMBL4072850 | 0.68 | MAPT (0.32) | MAPTKDM4EHSD17B10 | |
| SCHEMBL7256745 | 0.67 | PTGS2 (0.41) | CRHBPCRHR2LMNAMAPTHTT | |
| SCHEMBL11088564 | 0.67 | PTGS2 (0.40) | CRHBPCRHR2LMNAPTGS2BRD4 | |
| SCHEMBL5029403 | 0.65 | SMN1; SMN2 (0.38) | CRHBPCRHR2LMNAMAPTALDH1A1 | |
| SCHEMBL1469805 | 0.65 | CRHBP (0.40) | CRHBPCRHR2LMNAMAPTHTT | |
| SCHEMBL3686925 | 0.65 | ALDH1A1 (0.35) | CRHBPCRHR2LMNAPTGS2ALDH1A1 | |
| SCHEMBL9250727 | 0.65 | ALDH1A1 (0.35) | CRHBPCRHR2LMNAPTGS2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1812370-B1 | SYNTHESIS OF CYCLOPENTENONES | FIRMENICH & CIE (CH) | 2008-06-25 | — | — | EP | disclosed |
| US-7279605-B2 | Synthesis of cyclopentenones | FIRMENICH SA (CH) | 2007-10-09 | — | — | US | disclosed |
| US-20070197833-A1 | SYNTHESIS OF CYCLOPENTENONES | FIRMENICH SA (CH) | 2007-08-23 | — | — | US | disclosed |
| EP-1812370-A2 | SYNTHESIS OF CYCLOPENTENONES | FIRMENICH SA (CH) | 2007-08-01 | — | — | EP | disclosed |
| WO-2006051503-A2 | SYNTHESIS OF CYCLOPENTENONES | FIRMENICH SA (CH) | 2006-05-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197833-A1 | SYNTHESIS OF CYCLOPENTENONES | COASY, CBR3, PPIC | CRHBP 4186/4885CRHR2 3982/4885LMNA 3460/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.