Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 1/20 | 0.54 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.54 |
| ▸ | LDHA | P00338 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | TDO2 | P48775 | 2/20 | 0.46 |
| ▸ | HPGDS | O60760 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9968559 | 0.89 | HSD17B1 (0.64) | HSD17B1HSD17B2IDO1TDO2HPGDS | |
| SCHEMBL14973541 | 0.87 | HSD17B1 (0.51) | HSD17B1HSD17B2ALOX5MEN1NTSR1 | |
| SCHEMBL14983294 | 0.84 | HSD17B1 (0.51) | HSD17B1HSD17B2ALOX5KDM4EDYRK1A | |
| SCHEMBL12973036 | 0.82 | HPGDS (0.60) | HSD17B1HSD17B2LDHAHPGDSCYP11B1 | |
| SCHEMBL25118611 | 0.80 | HPGDS (0.58) | HSD17B1HSD17B2LDHAHPGDSCYP11B1 | |
| SCHEMBL913315 | 0.80 | HPGDS (0.58) | HSD17B1HSD17B2LDHAHPGDSCYP11B1 | |
| SCHEMBL29578423 | 0.80 | HPGDS (0.58) | HSD17B1HSD17B2LDHAHPGDSCYP11B1 | |
| SCHEMBL12523550 | 0.80 | HPGDS (0.58) | HSD17B1HSD17B2LDHAHPGDSCYP11B1 | |
| SCHEMBL903715 | 0.80 | HPGDS (0.58) | HSD17B1HSD17B2LDHAHPGDSCYP11B1 | |
| SCHEMBL12956772 | 0.79 | HSD17B1 (0.53) | HSD17B1HSD17B2LDHAHPGDSCYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8293898-B2 | Luminophores | UNIVERSITY OF YORK (GB) | 2012-10-23 | — | — | US | disclosed |
| US-20120157681-A1 | LUMINOPHORES | UNIVERSITY OF YORK (GB) | 2012-06-21 | — | — | US | disclosed |
| US-8106193-B2 | Luminophores | UNIVERSITY OF YORK (GB) | 2012-01-31 | — | — | US | disclosed |
| US-20100317851-A1 | LUMINOPHORES | UNIVERSITY OF YORK (GB) | 2010-12-16 | — | — | US | disclosed |
| EP-2207784-A1 | LUMINOPHORES | University of York (GB) | 2010-07-21 | — | — | EP | disclosed |
| WO-2009040551-A1 | LUMINOPHORES | UNIVERSITY OF YORK (GB) | 2009-04-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120157681-A1 | LUMINOPHORES | PPOX, CRY1, MPO | HSD17B1 1397/4885HSD17B2 1757/4885LDHA 240/4885 |
| US-20100317851-A1 | LUMINOPHORES | PPOX, CRY1, MPO | HSD17B1 1833/4885HSD17B2 1857/4885LDHA 217/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.