Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.65 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.61 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.52 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | METTL3 | Q86U44 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5029686 | 0.81 | PIK3CB (0.80) | HRH4PIK3CBACHESMN1; SMN2METTL3 | |
| SCHEMBL4896185 | 0.78 | HRH4 (0.75) | HRH4PIK3CBACHEMETTL3CYP1A2 | |
| SCHEMBL5029684 | 0.77 | PIK3CB (1.00) | HRH4PIK3CBACHEALDH1A1TSHR | |
| SCHEMBL14005278 | 0.72 | HRH4 (0.73) | HRH4PIK3CBACHEMETTL3CYP1A2 | |
| SCHEMBL1774199 | 0.70 | HRH4 (0.66) | HRH4PIK3CBSMN1; SMN2METTL3CYP1A2 | |
| SCHEMBL18362124 | 0.69 | LOXL2 (0.98) | SLC6A7LOXL2SMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL12321362 | 0.69 | FAAH (0.53) | HRH4SMN1; SMN2 | |
| SCHEMBL12321096 | 0.69 | FAAH (0.50) | HRH4LOXL2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL20337902 | 0.68 | LOXL2 (1.00) | SLC6A7LOXL2SMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL14421376 | 0.68 | SMN1; SMN2 (0.57) | HRH4PIK3CBSMN1; SMN2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080293711-A1 | Chemokine receptor modulators | METASTATIX, INC. | 2008-11-27 | — | — | US | disclosed |
| US-20080293711-A1 | Chemokine receptor modulators | METASTATIX, INC. | 2008-11-27 | — | — | US | disclosed |
| WO-2008112156-A1 | CHEMOKINE RECEPTOR MODULATORS | ALTIRIS THERAPEUTICS (US) | 2008-09-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293711-A1 | Chemokine receptor modulators | CCR5, CCL2, CXCR4 | HRH4 1565/4885PIK3CB 1550/4885SLC6A7 1585/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.