SCHEMBL9745609

SCHEMBL9745609

O=C(Cl)C1C=CC=CC1(F)OCc1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.41
SLC1A3 P43003 2/20 0.35
SLC1A2 P43004 2/20 0.35
SLC1A1 P43005 2/20 0.35
KMT2A Q03164 2/20 0.35
MEN1 O00255 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
L3MBTL1 Q9Y468 2/20 0.33
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
MAPK1 P28482 1/20 0.33
FABP7 O15540 1/20 0.33
FABP5 Q01469 1/20 0.33
SLC6A2 P23975 1/20 0.33
SLC6A3 Q01959 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
NR1H2 P55055 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5029772 0.89 SLC1A3 (0.37) ALDH1A1SLC1A3SLC1A2SLC1A1KMT2A
Hydrochloric Acid SCHEMBL9745618 0.88 SLC1A3 (0.36) ALDH1A1SLC1A3SLC1A2SLC1A1KMT2A
SCHEMBL2331142 0.81 ALDH1A1 (0.41) ALDH1A1SLC1A3SLC1A2SLC1A1KMT2A
SCHEMBL5284629 0.72 ALDH1A1 (0.39) ALDH1A1SLC1A3SLC1A2SLC1A1KMT2A
SCHEMBL7765472 0.71 KMT2A (0.36) ALDH1A1SLC1A3SLC1A2SLC1A1KMT2A
SCHEMBL23536852 0.70 ALDH1A1 (0.37) ALDH1A1SLC1A3SLC1A2SLC1A1KMT2A
SCHEMBL5150393 0.70 KMT2A (0.40) ALDH1A1SLC1A3SLC1A2SLC1A1KMT2A
SCHEMBL19285698 0.68 KMT2A (0.37) ALDH1A1SLC1A3SLC1A2SLC1A1KMT2A
SCHEMBL4216034 0.68 HSD11B1 (0.38) ALDH1A1KMT2AMEN1
SCHEMBL7132195 0.68 ALDH1A1 (0.38) ALDH1A1SLC1A3SLC1A2SLC1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5110496-A LIQUID CRYSTAL COMPOUND SHOWA SHELL SEKIYU KABUSHIKI KAISHA (JP) 1992-05-05 US disclosed
EP-0445037-A2 Liquid crystal compound Showa Shell Sekiyu Kabushiki Kaisha (JP) 1991-09-04 EP disclosed