Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5029772 | 0.70 | SLC1A3 (0.37) | KMT2ASLC1A3SLC1A2SLC1A1CYP2C19 | |
| Hydrochloric Acid SCHEMBL9745618 | 0.69 | SLC1A3 (0.36) | KMT2ASLC1A3SLC1A2SLC1A1CYP2C19 | |
| SCHEMBL20523503 | 0.69 | SLC1A3 (0.37) | KMT2ASLC1A3SLC1A2SLC1A1CYP2C19 | |
| SCHEMBL9745609 | 0.68 | ALDH1A1 (0.41) | KMT2ASLC1A3SLC1A2SLC1A1CYP2C19 | |
| SCHEMBL21712684 | 0.61 | SLC1A3 (0.37) | KMT2ASLC1A3SLC1A2SLC1A1CYP2C19 | |
| SCHEMBL4038161 | 0.60 | KMT2A (0.47) | KMT2ASLC1A3SLC1A2SLC1A1CYP2C19 | |
| Urea SCHEMBL28054623 | 0.59 | TSHR (0.71) | KMT2ASLC1A3SLC1A2SLC1A1CYP2C19 | |
| Carbamic Acid SCHEMBL119806 | 0.59 | TSHR (0.71) | KMT2ASLC1A3SLC1A2SLC1A1CYP2C19 | |
| SCHEMBL7765472 | 0.59 | KMT2A (0.36) | KMT2ASLC1A3SLC1A2SLC1A1CYP2C19 | |
| SCHEMBL19745328 | 0.58 | SLC1A3 (0.45) | KMT2ASLC1A3SLC1A2SLC1A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3419967-A1 | SYNTHETIC PROCESSES AND INTERMEDIATES | Taxis Pharmaceuticals, Inc. (US) | 2019-01-02 | — | — | EP | disclosed |
| WO-2017147316-A1 | SYNTHETIC PROCESSES AND INTERMEDIATES | TAXIS PHARMACEUTICALS, INC. (US) | 2017-08-31 | — | — | WO | disclosed |