SCHEMBL3108980

SCHEMBL3108980

CO[Si](OC)(OC)c1c(C)cc(C)cc1C

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.39
RAPGEF4 Q8WZA2 3/20 0.36
KDM4E B2RXH2 1/20 0.36
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
GAA P10253 1/20 0.36
MAPT P10636 1/20 0.36
NOS3 P29474 1/20 0.31
NOS1 P29475 1/20 0.31
NOS2 P35228 1/20 0.31
KMT2A Q03164 1/20 0.31
CYP1A2 P05177 1/20 0.30
CYP2A6 P11509 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13027094 0.84 ACHE (0.52) ACHEKDM4EALDH1A1LMNAMAPT
SCHEMBL13027086 0.80 ALDH1A1 (0.46) ACHEALDH1A1MAPTKMT2A
SCHEMBL2425702 0.79 RAPGEF4 (0.36) ACHERAPGEF4KDM4EALDH1A1LMNA
SCHEMBL13027108 0.75 ACHE (0.58) ACHEKDM4EALDH1A1GAAMAPT
SCHEMBL5031080 0.74 CYP1A2 (0.39) ACHEALDH1A1LMNACYP1A2CYP2A6
SCHEMBL2478476 0.73 NOS3 (0.33) RAPGEF4KDM4EALDH1A1LMNAGAA
SCHEMBL5552255 0.73 KDM4E (0.32) RAPGEF4KDM4EALDH1A1LMNAGAA
SCHEMBL5032243 0.73 FFAR4 (0.34) RAPGEF4KDM4EALDH1A1LMNAGAA
SCHEMBL13027082 0.73 ACHE (0.34) ACHERAPGEF4KDM4EALDH1A1LMNA
SCHEMBL13027100 0.72 ACHE (0.43) ACHERAPGEF4KDM4EALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112142660-B Method for simply, conveniently and efficiently synthesizing 4-aryl butyric acid derivative 淮阴师范学院 2021-11-23 CN claimed
CN-112142660-A Method for simply, conveniently and efficiently synthesizing 4-aryl butyric acid derivative 淮阴师范学院 2020-12-29 CN claimed
WO-2024190380-A1 SILICON-CONTAINING RESIN COMPOSITION PURIFIED PRODUCT MANUFACTURING METHOD, PATTERN FORMATION METHOD, AND SILICON-CONTAINING RESIN COMPOSITION PURIFIED PRODUCT 東京応化工業株式会社 2024-09-19 WO disclosed
CN-112142660-B Method for simply, conveniently and efficiently synthesizing 4-aryl butyric acid derivative 淮阴师范学院 2021-11-23 CN disclosed
CN-112142660-A Method for simply, conveniently and efficiently synthesizing 4-aryl butyric acid derivative 淮阴师范学院 2020-12-29 CN disclosed
US-10234762-B2 Pattern-forming method JSR CORPORATION (JP) 2019-03-19 US disclosed
US-10025188-B2 Resist pattern-forming method JSR CORPORATION (JP) 2018-07-17 US disclosed
US-20170322492-A1 RESIST PATTERN-FORMING METHOD JSR CORPORATION (JP) 2017-11-09 US disclosed
US-20170003592-A1 PATTERN-FORMING METHOD JSR CORPORATION (JP) 2017-01-05 US disclosed
US-9434609-B2 Method for forming pattern, and polysiloxane composition JSR CORPORATION (JP) 2016-09-06 US disclosed
US-9329478-B2 Polysiloxane composition and pattern-forming method JSR CORPORATION (JP) 2016-05-03 US disclosed
US-7291747-B2 Silicon compounds and process for preparation thereof CHISSO CORPORATION (JP) 2007-11-06 US disclosed
WO-2007106348-A2 ZIEGLER-NATTA CATALYST WITH IN SITU-GENERATED DONOR NOVOLEN TECHNOLOGY HOLDINGS C.V. (NL) 2007-09-20 WO disclosed
US-20070213204-A1 Ziegler-Natta catalyst with in situ-generated donor NOVOLEN TECHNOLOGY HOLDINGS C.V. 2007-09-13 US disclosed
US-20040143081-A1 Novel silicon compounds and process for preparation thereof JNC CORPORATION (JP) 2004-07-22 US disclosed
EP-0790260-B1 Solid catalyst components for polymerization JAPAN POLYOLEFINS CO LTD (JP) 2002-11-06 EP disclosed
EP-1141044-A1 SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, CATALYST FOR OLEFIN POLYMERIZATION AND PROCESS FOR PRODUCING OLEFIN POLYMER Basell Technology Company B.V. (NL) 2001-10-10 EP disclosed
WO-2001036496-A1 SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, CATALYST FOR OLEFIN POLYMERIZATION AND PROCESS FOR PRODUCING OLEFIN POLYMER BASELL TECHNOLOGY COMPANY B.V. (NL) 2001-05-25 WO disclosed
US-5902765-A MADE BY REACTING A MAGNESIUM DIHALIDE WITH TETRAHYDROFURAN, BUTYL ETHER OR DIETHYL ETHER AND TREATING THE SOLID SUBSTANCE WITH AN ELECTRON DONATIVE COMPOUND HAVING TWO OR MORE ALKOXY OR ESTER GROUPS, CONTACTING WITH TITANIUM; STEREOREGULARITY JAPAN POLYOLEFINS CO., LTD. (JP) 1999-05-11 US disclosed
EP-0790260-A1 Solid catalyst components for polymerization JAPAN POLYOLEFINS CO., LTD. (JP) 1997-08-20 EP disclosed