SCHEMBL5030144

SCHEMBL5030144

O=[N+]([O-])c1ccc2c(c1)Cc1cc([N+](=O)[O-])c([N+](=O)[O-])cc1-2

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TLR9 Q9NR96 2/20 0.66
MEN1 O00255 1/20 0.66
LMNA P02545 1/20 0.66
MAPT P10636 1/20 0.66
RAB9A P51151 1/20 0.66
KMT2A Q03164 1/20 0.66
TDP2 O95551 1/20 0.54
PGR P06401 2/20 0.52
CRHBP P24387 1/20 0.50
CRHR2 Q13324 1/20 0.50
HSP90AA1 P07900 1/20 0.50
PTPRC P08575 1/20 0.46
S100A4 P26447 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
ADRA2A P08913 2/20 0.45
PNMT P11086 2/20 0.45
PARP1 P09874 1/20 0.45
ALDH1A1 P00352 3/20 0.44
GPR35 Q9HC97 2/20 0.44
TP53 P04637 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30049268 0.89 TLR9 (0.79) TLR9MEN1LMNAMAPTRAB9A
SCHEMBL987760 0.89 TLR9 (0.79) TLR9MEN1LMNAMAPTRAB9A
SCHEMBL8928040 0.84 LMNA (0.55) TLR9MEN1LMNAMAPTRAB9A
2-Nitrofluorene SCHEMBL644332 0.81 MAPT (0.68) TLR9MEN1LMNAMAPTRAB9A
2-Nitrofluorene SCHEMBL29450702 0.81 MAPT (0.68) TLR9MEN1LMNAMAPTRAB9A
SCHEMBL8088143 0.80 TLR9 (0.62) TLR9MEN1LMNAMAPTRAB9A
SCHEMBL30785663 0.80 TLR9 (0.58) TLR9MEN1LMNAMAPTRAB9A
SCHEMBL9811059 0.80 TLR9 (0.62) TLR9MEN1LMNAMAPTRAB9A
SCHEMBL252575 0.80 TLR9 (0.58) TLR9MEN1LMNAMAPTRAB9A
SCHEMBL2374341 0.79 MAPT (1.00) TLR9MEN1LMNAMAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1992999-B1 Image carrier and damping member therefor RICOH CO LTD (JP) 2013-10-16 EP disclosed
CN-101685278-B Image carrier and damping member therefor RICOH CO LTD 2012-07-25 CN disclosed
CN-101685278-A Image carrier and damping member therefor RICOH KK 2010-03-31 CN disclosed
EP-1992999-A2 Image carrier and damping member therefor Ricoh Company, Ltd. (JP) 2008-11-19 EP disclosed
US-6757508-B2 Image carrier and damping member therefor RICOH COMPANY, LTD. (JP) 2004-06-29 US disclosed
CN-1387091-A Image carrier and damping member thereof RICOH KK (JP) 2002-12-25 CN disclosed
US-20020186985-A1 Image carrier and damping member therefor RICOH COMPANY, LTD. (JP) 2002-12-12 US disclosed
EP-1260875-A1 Image carrier and damping member therefor Ricoh Company, Ltd. (JP) 2002-11-27 EP disclosed