Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 3/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5027934 | 0.74 | SMYD2 (0.39) | ALDH1A1HSD17B10KDM4EMEN1KMT2A | |
| SCHEMBL4590746 | 0.73 | HPGD (0.38) | ALDH1A1KDM4EPOLBMEN1KMT2A | |
| SCHEMBL4590748 | 0.72 | ALDH1A1 (0.35) | ALDH1A1HSD17B10KDM4EPOLBMEN1 | |
| SCHEMBL4574556 | 0.72 | HPGD (0.38) | ALDH1A1KDM4EPOLBMEN1KMT2A | |
| SCHEMBL18270226 | 0.72 | ALDH1A1 (0.35) | ALDH1A1KDM4EPOLBMEN1KMT2A | |
| SCHEMBL9175019 | 0.69 | LMNA (0.32) | ALDH1A1LMNAHPGDTSHR | |
| SCHEMBL25860125 | 0.69 | ALDH1A1 (0.42) | ALDH1A1HSD17B10KDM4EPOLBMEN1 | |
| SCHEMBL3180873 | 0.68 | ALDH1A1 (0.40) | ALDH1A1HSD17B10KDM4EPOLBMEN1 | |
| SCHEMBL7479973 | 0.67 | LMNA (0.30) | LMNA | |
| SCHEMBL5028036 | 0.67 | SMYD2 (0.38) | ALDH1A1HSD17B10KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008080986-A1 | FURAN DERIVATIVES, METHOD OF SYNTHESIS AND USES THEREOF | NEUROPHARMA, S.A. (ES) | 2008-07-10 | — | — | WO | disclosed |
| EP-1939191-A1 | Furan derivatives, method of synthesis and uses thereof | Neuropharma S.A. (ES) | 2008-07-02 | — | — | EP | disclosed |