Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | USP2 | O75604 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4574556 | 0.96 | HPGD (0.38) | HPGDMAPTSMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL11265902 | 0.78 | SOAT1 (0.42) | MAPTSMN1; SMN2HTTALDH1A1CYP3A4 | |
| SCHEMBL3481385 | 0.78 | LTA4H (0.39) | CYP1A2CYP2C19CYP2C9CYP3A4TDP1 | |
| SCHEMBL707442 | 0.78 | LTA4H (0.43) | CYP1A2CYP2C19CYP2C9ALDH1A1CYP3A4 | |
| SCHEMBL706314 | 0.78 | LTA4H (0.43) | CYP1A2CYP2C19CYP2C9ALDH1A1CYP3A4 | |
| SCHEMBL4590748 | 0.78 | ALDH1A1 (0.35) | HPGDMAPTSMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL704016 | 0.76 | LTA4H (0.44) | CYP1A2CYP2C19CYP2C9ALDH1A1CYP3A4 | |
| SCHEMBL4590392 | 0.76 | LTA4H (0.35) | SMN1; SMN2ALDH1A1CYP3A4TDP1MAPK1 | |
| SCHEMBL5028036 | 0.76 | SMYD2 (0.38) | HPGDMAPTSMN1; SMN2HTTALDH1A1 | |
| SCHEMBL702747 | 0.75 | LTA4H (0.43) | CYP1A2CYP2C19CYP2C9ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008080988-A2 | CYCLOPENTANONE DERIVATIVES, METHOD OF SYNTHESIS AND USES THEREOF | NEUROPHARMA, S.A. (ES) | 2008-07-10 | — | — | WO | disclosed |