Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ANPEP | P15144 | 1/20 | 0.32 |
| ▸ | LAP3 | P28838 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18270226 | 0.82 | ALDH1A1 (0.35) | LMNAMAOAALDH1A1HPGDTSHR | |
| SCHEMBL7479973 | 0.76 | LMNA (0.30) | LMNA | |
| SCHEMBL8003670 | 0.75 | ELANE (0.37) | LMNAATMALDH1A1TSHR | |
| SCHEMBL13621397 | 0.75 | TP53 (0.36) | LMNAALDH1A1HPGDESR1ESR2 | |
| SCHEMBL3885758 | 0.75 | MAOA (0.35) | TAAR1SLC6A2MAOASLC6A4SLC6A3 | |
| SCHEMBL9459938 | 0.73 | ALDH1A3 (0.45) | LMNACYP2A6ALDH1A1HPGD | |
| SCHEMBL301746 | 0.72 | LMNA (0.31) | LMNATAAR1SLC6A2MAOASLC6A4 | |
| SCHEMBL8536402 | 0.71 | LMNA (0.35) | LMNAANPEPLAP3ALDH1A1HPGD | |
| SCHEMBL1315704 | 0.71 | AOC3 (0.33) | TAAR1SLC6A2MAOASLC6A4SLC6A3 | |
| SCHEMBL273159 | 0.71 | ESR1 (0.35) | LMNATAAR1SLC6A2MAOASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3271468-A1 | DEAMINATION OF ORGANOPHOSPHORUS-NUCLEOSIDES | Institut Univ. de Ciència i Tecnologia, S.A. (ES) | 2018-01-24 | — | — | EP | disclosed |
| WO-2017040449-A1 | TRIAZOLOPYRIDINE INHIBITORS OF MYELOPEROXIDASE | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-03-09 | — | — | WO | disclosed |
| WO-2016146808-A1 | DEAMINATION OF ORGANOPHOSPHORUS-NUCLEOSIDES | INSTITUT UNIV. DE CIÈNCIA I TECNOLOGIA, S. A. (ES) | 2016-09-22 | — | — | WO | disclosed |
| EP-2970344-A2 | METHODS FOR THE SYNTHESIS OF SPHINGOMYELINS AND DIHYDROSPHINGOMYELINS | Cerenis Therapeutics Holding SA (FR) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014140787-A2 | METHODS FOR THE SYNTHESIS OF SPHINGOMYELINS AND DIHYDROSPHINGOMYELINS | CERENIS THERAPEUTICS HOLDING SA (FR) | 2014-09-18 | — | — | WO | disclosed |
| EP-0529528-B1 | Novel vitamin D3 analogues | DAIKIN IND LTD (JP) | 1995-04-19 | — | — | EP | disclosed |
| EP-0593464-A1 | BENZOIC ACID DERIVATIVES and their use as LTB4 inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 1994-04-27 | — | — | EP | disclosed |
| US-5210237-A | VITAMIN D3 ANALOGUES | DAIKIN INDUSTRIES, LTD. (JP) | 1993-05-11 | — | — | US | disclosed |
| EP-0529528-A2 | Novel vitamin D3 analogues | DAIKIN INDUSTRIES, LTD. (JP) | 1993-03-03 | — | — | EP | disclosed |
| EP-0593464-A4 | BENZOIC ACID DERIVATIVES. | SMITHKLINE BEECHAM CORP (US) | 1993-02-12 | — | — | EP | disclosed |
| WO-1991018601-A1 | BENZOIC ACID DERIVATIVES | SMITHKLINE BEECHAM CORPORATION (US) | 1991-12-12 | — | — | WO | disclosed |