Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CCNK | O75909 | 1/20 | 0.32 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1317031 | 0.79 | LTA4H (0.40) | ALDH1A1TDP1MAPK1CYP1A2CYP2C9 | |
| SCHEMBL4590746 | 0.78 | HPGD (0.38) | ALDH1A1HPGDCYP3A4ALOX15USP2 | |
| SCHEMBL5028036 | 0.75 | SMYD2 (0.38) | ALDH1A1HPGDCYP3A4ALOX15USP2 | |
| SCHEMBL4574556 | 0.74 | HPGD (0.38) | ALDH1A1HPGDCYP3A4ALOX15USP2 | |
| SCHEMBL1315239 | 0.73 | — | — | |
| SCHEMBL1314751 | 0.72 | LMNA (0.32) | TSHR | |
| SCHEMBL5030652 | 0.72 | ALDH1A1 (0.34) | ALDH1A1HPGDCYP3A4ALOX15USP2 | |
| SCHEMBL1315769 | 0.72 | — | — | |
| SCHEMBL5030044 | 0.71 | ALDH1A1 (0.39) | ALDH1A1HPGDCYP3A4ALOX15USP2 | |
| SCHEMBL5026143 | 0.70 | ALDH1A1 (0.41) | ALDH1A1HPGDCYP3A4ALOX15USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008080988-A2 | CYCLOPENTANONE DERIVATIVES, METHOD OF SYNTHESIS AND USES THEREOF | NEUROPHARMA, S.A. (ES) | 2008-07-10 | — | — | WO | disclosed |