Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX2 | Q96LB1 | 4/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6276772 | 0.85 | OPRM1 (0.39) | MRGPRX2OPRM1OPRD1OPRK1SIGMAR1 | |
| SCHEMBL14492610 | 0.79 | CCR2 (0.37) | — | |
| SCHEMBL28298759 | 0.78 | CA12 (0.34) | OPRM1OPRD1OPRK1SIGMAR1 | |
| SCHEMBL18540416 | 0.78 | HTR2C (0.40) | OPRM1OPRD1OPRK1 | |
| SCHEMBL13948527 | 0.78 | HTR2C (0.40) | OPRM1OPRD1OPRK1 | |
| SCHEMBL674309 | 0.77 | ESR2 (0.41) | OPRM1OPRD1OPRK1 | |
| SCHEMBL29374049 | 0.77 | ESR2 (0.41) | OPRM1OPRD1OPRK1 | |
| SCHEMBL5706922 | 0.76 | MRGPRX2 (0.49) | MRGPRX2OPRM1OPRD1OPRK1SIGMAR1 | |
| SCHEMBL4521166 | 0.76 | OPRK1 (0.45) | MRGPRX2OPRM1OPRD1OPRK1 | |
| SCHEMBL9264554 | 0.73 | ESR1 (0.41) | MRGPRX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008019152-A1 | COMPOSITION, ASSOCIATED METHOD AND ARTICLE | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2008-02-14 | — | — | WO | disclosed |