Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 5/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | MRGPRX2 | Q96LB1 | 4/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5030707 | 0.85 | MRGPRX2 (0.40) | OPRM1OPRD1OPRK1MRGPRX2SIGMAR1 | |
| SCHEMBL24000928 | 0.78 | HTR2C (0.44) | — | |
| SCHEMBL29859799 | 0.78 | CA12 (0.41) | OPRM1OPRD1OPRK1SIGMAR1 | |
| SCHEMBL23501557 | 0.78 | CA12 (0.41) | OPRM1OPRD1OPRK1SIGMAR1 | |
| SCHEMBL14433230 | 0.76 | POLB (0.36) | — | |
| SCHEMBL17530495 | 0.76 | MAPT (0.42) | — | |
| SCHEMBL11438868 | 0.75 | HPGD (0.36) | — | |
| SCHEMBL13006941 | 0.74 | ALDH1A1 (0.35) | — | |
| SCHEMBL9906973 | 0.73 | RXRA (0.39) | — | |
| SCHEMBL4521166 | 0.73 | OPRK1 (0.45) | OPRM1OPRD1OPRK1MRGPRX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-55076831-A | — | — | None | — | — | JP | disclosed |
| JP-55013207-A | — | — | None | — | — | JP | disclosed |
| EP-1597006-A2 | WEATHERABLE MULTILAYER ARTICLES AND METHOD FOR THEIR PREPARATION | GENERAL ELECTRIC COMPANY (US) | 2005-11-23 | — | — | EP | disclosed |
| WO-2004085102-A2 | WEATHERABLE MULTILAYER ARTICLES AND METHOD FOR THEIR PREPARATION | GENERAL ELECTRIC COMPANY (US) | 2004-10-07 | — | — | WO | disclosed |
| JP-S5576831-A | HYDROXYINDENE DIMER AND ITS PREPARATION | MITSUI TOATSU CHEM INC | 1980-06-10 | — | — | JP | disclosed |
| JP-S5513207-A | NOVEL INDANE COMPOUND AND ITS PREPARATION | MITSUI TOATSU CHEM INC | 1980-01-30 | — | — | JP | disclosed |