SCHEMBL5030745

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5126561	0.80	ALDH1A1 (0.47)	DGAT1GAAALDH1A1HPGDCYP1A2
	SCHEMBL5027375	0.79	NPC1 (0.55)	DGAT1GAAALDH1A1HPGDMAPT
	SCHEMBL13588594	0.77	JAK2 (0.72)	FLT1KDRJAK2JAK3
	SCHEMBL5033875	0.76	MCL1 (0.40)	GAAALDH1A1HPGDCYP1A2MAPT
	SCHEMBL5052668	0.72	ADORA3 (0.50)	ALDH1A1HPGDMAPTSMN1; SMN2RAB9A
	SCHEMBL12661996	0.71	PARP1 (0.41)	GAAALDH1A1HPGDCYP1A2KDR
	SCHEMBL14360826	0.70	TYK2 (0.46)	MAPTSMN1; SMN2RAB9ANPC1KDM4E
	SCHEMBL5032088	0.69	MCL1 (0.41)	GAAALDH1A1MAPTSMN1; SMN2RAB9A
	SCHEMBL2891693	0.69	TYK2 (0.41)	CYP1A2RAB9ANPC1KDM4E
	SCHEMBL5029502	0.69	CYP11B2 (0.46)	CYP1A2IRAK4MAPTKDRRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.