Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NQO1 | P15559 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | APAF1 | O14727 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17299128 | 0.81 | KMT2A (0.36) | HTTKMT2ANQO1MAPTL3MBTL1 | |
| SCHEMBL10397963 | 0.78 | NQO2 (0.33) | — | |
| SCHEMBL17298243 | 0.77 | NOS3 (0.38) | HTTKMT2ANQO1MAPTL3MBTL1 | |
| SCHEMBL2400774 | 0.74 | HTT (0.39) | HTTKMT2ANQO1MAPTGAA | |
| SCHEMBL29693601 | 0.74 | LMNA (0.46) | HTTKMT2ANQO1MAPTGAA | |
| SCHEMBL2401968 | 0.74 | LMNA (0.46) | HTTKMT2ANQO1MAPTGAA | |
| SCHEMBL30859069 | 0.74 | HTT (0.44) | HTTKMT2ANQO1MAPTGAA | |
| SCHEMBL20743143 | 0.72 | HTT (0.42) | HTTKMT2ANQO1MAPTL3MBTL1 | |
| SCHEMBL29951476 | 0.70 | HTT (0.37) | HTTKMT2A | |
| SCHEMBL4051209 | 0.69 | ALDH1A1 (0.47) | KMT2AMAPTTDP1MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0199060-A2 | Pyridyl phosphoric-acid esters | Shell Agrar GmbH & Co. KG (DE) | 1986-10-29 | — | — | EP | claimed |
| EP-2404918-B1 | PYRIDINE DERIVATIVE AS PPARY INHIBITOR | DAIICHI SANKYO CO LTD (JP) | 2016-11-30 | — | — | EP | disclosed |
| US-8946264-B2 | Pyridine derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2015-02-03 | — | — | US | disclosed |
| US-20130204009-A1 | PROCESS FOR PREPARING BENZOIC ACID ESTERS | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-08-08 | — | — | US | disclosed |
| EP-2615081-A1 | PROCESS FOR PREPARING BENZOIC ACID ESTERS | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-07-17 | — | — | EP | disclosed |
| US-20130045994-A1 | PYRIDINE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-02-21 | — | — | US | disclosed |
| US-20120029026-A1 | PYRIDINE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-02-02 | — | — | US | disclosed |
| EP-2404918-A1 | PYRIDINE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2012-01-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130204009-A1 | PROCESS FOR PREPARING BENZOIC ACID ESTERS | HPD, CYP2B6, PAH | HTT 1699/4885KMT2A 825/4885NQO1 1466/4885 |
| US-20120029026-A1 | PYRIDINE DERIVATIVE | PPARD, PPARG, PPARA | HTT 3517/4885KMT2A 3426/4885NQO1 657/4885 |
| US-20130045994-A1 | PYRIDINE DERIVATIVE | PPARD, PPARG, PPARA | HTT 3517/4885KMT2A 3426/4885NQO1 657/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.