Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRG2 | P18507 | 1/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | DHPS | P49366 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 4/20 | 0.40 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9971217 | 0.91 | CTDSP1 (0.47) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| SCHEMBL2474963 | 0.84 | ALDH1A1 (0.54) | ALDH1A1KDM4EHPGDSMN1; SMN2FYN | |
| SCHEMBL9968554 | 0.84 | KDM4E (0.43) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| SCHEMBL14973723 | 0.83 | KDM4E (0.47) | ALDH1A1KDM4EHPGDGAASMN1; SMN2 | |
| SCHEMBL30102577 | 0.78 | HDAC8 (0.52) | GABRG2GABRB3GABRA5GABRA3ALDH1A1 | |
| SCHEMBL28965201 | 0.78 | HDAC8 (0.52) | GABRG2GABRB3GABRA5GABRA3ALDH1A1 | |
| SCHEMBL502772 | 0.76 | FYN (0.47) | GABRG2GABRB3GABRA5GABRA3PLK1 | |
| SCHEMBL2479831 | 0.74 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| SCHEMBL15425095 | 0.73 | MAPT (0.54) | KDM4EHPGDTSHRLMNAGAA | |
| SCHEMBL14983300 | 0.71 | PDE3B (0.46) | ALDH1A1KDM4EHPGDPDE3ANEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8293898-B2 | Luminophores | UNIVERSITY OF YORK (GB) | 2012-10-23 | — | — | US | disclosed |
| US-8293898-B2 | Luminophores | UNIVERSITY OF YORK (GB) | 2012-10-23 | — | — | US | disclosed |
| US-8293898-B2 | Luminophores | UNIVERSITY OF YORK (GB) | 2012-10-23 | — | — | US | disclosed |
| US-20120157681-A1 | LUMINOPHORES | UNIVERSITY OF YORK (GB) | 2012-06-21 | — | — | US | disclosed |
| US-20120157681-A1 | LUMINOPHORES | UNIVERSITY OF YORK (GB) | 2012-06-21 | — | — | US | disclosed |
| US-20120157681-A1 | LUMINOPHORES | UNIVERSITY OF YORK (GB) | 2012-06-21 | — | — | US | disclosed |
| US-8106193-B2 | Luminophores | UNIVERSITY OF YORK (GB) | 2012-01-31 | — | — | US | disclosed |
| US-8106193-B2 | Luminophores | UNIVERSITY OF YORK (GB) | 2012-01-31 | — | — | US | disclosed |
| US-8106193-B2 | Luminophores | UNIVERSITY OF YORK (GB) | 2012-01-31 | — | — | US | disclosed |
| US-20100317851-A1 | LUMINOPHORES | UNIVERSITY OF YORK (GB) | 2010-12-16 | — | — | US | disclosed |
| US-20100317851-A1 | LUMINOPHORES | UNIVERSITY OF YORK (GB) | 2010-12-16 | — | — | US | disclosed |
| US-20100317851-A1 | LUMINOPHORES | UNIVERSITY OF YORK (GB) | 2010-12-16 | — | — | US | disclosed |
| EP-2207784-A1 | LUMINOPHORES | University of York (GB) | 2010-07-21 | — | — | EP | disclosed |
| WO-2009040551-A1 | LUMINOPHORES | UNIVERSITY OF YORK (GB) | 2009-04-02 | — | — | WO | disclosed |
| WO-2009040551-A1 | LUMINOPHORES | UNIVERSITY OF YORK (GB) | 2009-04-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120157681-A1 | LUMINOPHORES | PPOX, CRY1, MPO | GABRG2 3425/4885GABRB3 4231/4885GABRA5 4406/4885 |
| US-20100317851-A1 | LUMINOPHORES | PPOX, CRY1, MPO | GABRG2 3378/4885GABRB3 4064/4885GABRA5 4261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.