Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | NEK2 | P51955 | 2/20 | 0.41 |
| ▸ | FYN | P06241 | 7/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | TYK2 | P29597 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9971217 | 0.92 | CTDSP1 (0.47) | KDM4EALDH1A1HPGDLMNATSHR | |
| SCHEMBL503126 | 0.84 | GABRG2 (0.44) | KDM4EALDH1A1HPGDLMNATSHR | |
| SCHEMBL2474963 | 0.83 | ALDH1A1 (0.54) | KDM4EALDH1A1HPGDNEK2FYN | |
| SCHEMBL14973723 | 0.82 | KDM4E (0.47) | KDM4EALDH1A1HPGDNEK2FYN | |
| SCHEMBL9968558 | 0.77 | BRD4 (0.47) | FYNMAP3K11BMPR1ATGFBR1ACVRL1 | |
| SCHEMBL9968556 | 0.75 | KDM4E (0.38) | KDM4EALDH1A1HPGDLMNATSHR | |
| SCHEMBL2479831 | 0.73 | ALDH1A1 (0.50) | KDM4EALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL13881644 | 0.71 | FYN (0.40) | CTDSP1NEK2FYNBMPR1ATGFBR1 | |
| SCHEMBL14973495 | 0.70 | KDM4E (0.44) | KDM4EALDH1A1HPGDLMNAHSD17B10 | |
| SCHEMBL14983300 | 0.70 | PDE3B (0.46) | KDM4EALDH1A1HPGDNEK2MAP3K11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8293898-B2 | Luminophores | UNIVERSITY OF YORK (GB) | 2012-10-23 | — | — | US | disclosed |
| US-20120157681-A1 | LUMINOPHORES | UNIVERSITY OF YORK (GB) | 2012-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120157681-A1 | LUMINOPHORES | PPOX, CRY1, MPO | KDM4E 4729/4885ALDH1A1 70/4885HPGD 1428/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.