Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5C | P41229 | 4/20 | 0.55 |
| ▸ | FTO | Q9C0B1 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | KDM6B | O15054 | 3/20 | 0.55 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.55 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.55 |
| ▸ | KDM3A | Q9Y4C1 | 3/20 | 0.55 |
| ▸ | KDM4A | O75164 | 3/20 | 0.55 |
| ▸ | ALKBH5 | Q6P6C2 | 2/20 | 0.55 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.55 |
| ▸ | TET3 | O43151 | 1/20 | 0.55 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | KDM5A | P29375 | 1/20 | 0.55 |
| ▸ | ASPH | Q12797 | 1/20 | 0.55 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.55 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.55 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.55 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29427285 | 1.00 | KDM5C (0.55) | KDM5CFTOKDM4EKDM6BKDM4C | |
| Trifluoroacetic Acid SCHEMBL20522759 | 0.95 | KDM4E (0.50) | KDM5CFTOKDM4EKDM6BKDM4C | |
| Alcohol SCHEMBL28244007 | 0.92 | KDM4C (0.47) | KDM5CFTOKDM4EKDM6BKDM4C | |
| SCHEMBL16094544 | 0.87 | KDM4C (0.53) | KDM5CFTOKDM4EKDM6BKDM4C | |
| SCHEMBL28019417 | 0.86 | VNN1 (0.58) | VNN1SMARCA2SMARCA4LOXL2HDAC4 | |
| SCHEMBL30893039 | 0.85 | KDM4C (0.52) | KDM5CFTOKDM4EKDM6BKDM4C | |
| SCHEMBL16036217 | 0.85 | KDM4C (0.52) | KDM5CFTOKDM4EKDM6BKDM4C | |
| SCHEMBL25221330 | 0.83 | VNN1 (0.46) | VNN1SMARCA2SMARCA4LOXL2HDAC4 | |
| SCHEMBL16690807 | 0.83 | SMARCA2 (0.49) | SYKVNN1SMARCA2SMARCA4LOXL2 | |
| SCHEMBL29427234 | 0.83 | LOXL2 (0.49) | KDM5CKDM5BSYKVNN1SMARCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 523 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230295138-A1 | HETEROCYCLYL PYRIDINES AS NOVEL FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2023-09-21 | — | — | US | claimed |
| EP-4161914-A1 | HETEROCYCLYL PYRIDINES AS NOVEL FUNGICIDES | Bayer Aktiengesellschaft (DE) | 2023-04-12 | — | — | EP | claimed |
| CN-104781236-B | The method for preparing 2- trifluoromethyls isonicotinic acid and ester | 霍夫曼-拉罗奇有限公司 | 2018-04-24 | — | — | CN | claimed |
| EP-2920150-B1 | PROCESS FOR THE PREPARATION OF 2-TRIFLUOROMETHYL ISONICOTINIC ACID AND ESTERS | HOFFMANN LA ROCHE (CH) | 2017-07-19 | — | — | EP | claimed |
| US-9481650-B2 | Process for the preparation of 2-trifluoromethyl isonicotinic acid and esters | HOFFMANN LA ROCHE INC. (US) | 2016-11-01 | — | — | US | claimed |
| US-20150291530-A1 | PROCESS FOR THE PREPARATION OF 2-TRIFLUOROMETHYL ISONICOTINIC ACID AND ESTERS | HOFFMANN-LA ROCHE INC. (US) | 2015-10-15 | — | — | US | claimed |
| EP-2920150-A1 | PROCESS FOR THE PREPARATION OF 2-TRIFLUOROMETHYL ISONICOTINIC ACID AND ESTERS | F. Hoffmann-La Roche AG (CH) | 2015-09-23 | — | — | EP | claimed |
| WO-2014076127-A1 | PROCESS FOR THE PREPARATION OF 2-TRIFLUOROMETHYL ISONICOTINIC ACID AND ESTERS | F. HOFFMANN-LA ROCHE AG (CH) | 2014-05-22 | — | — | WO | claimed |
| EP-4406387-B1 | AN ORGANIC ELECTRONIC DEVICE COMPRISING A SUBSTRATE, AN ANODE LAYER, A CATHODE LAYER, AT LEAST ONE FIRST EMISSION LAYER, AND A HOLE INJECTION LAYER, WHEREIN THE HOLE INJECTION LAYER COMPRISES A METAL COMPLEX OF FORMULA (I) AND A COMPOUND OF FORMULA (II), WHEREIN THE HOLE INJECTION LAYER IS ARRANGED BETWEEN THE ANODE LAYER AND THE AT LEAST ONE FIRST EMISSION LAYER | NOVALED GMBH (DE) | 2026-05-20 | — | — | EP | disclosed |
| US-12630533-B2 | Heterocyclic compounds useful as KCNT1 inhibitors | ACTIO BIOSCIENCES, INC. (US) | 2026-05-19 | — | — | US | disclosed |
| US-20260085073-A1 | PYRAZOLYLCARBOXAMIDE COMPOUNDS AND THEIR USE IN THERAPY | HOTSPOT THERAPEUTICS INC (US) | 2026-03-26 | — | — | US | disclosed |
| US-12583849-B2 | KCNT1 inhibitors and methods of use | PRAXIS PRECISION MEDICINES, INC. (US) | 2026-03-24 | — | — | US | disclosed |
| US-12552748-B2 | Pyridine (thio)amides as fungicidal compounds | BAYER AKTIENGESELLSCHAFT (DE) | 2026-02-17 | — | — | US | disclosed |
| EP-4692069-A2 | KCNT1 INHIBITORS AND METHODS OF USE | Praxis Precision Medicines, Inc. (US) | 2026-02-11 | — | — | EP | disclosed |
| US-5856349-A | 2-Saccharinylmethyl heterocyclic carboxylates useful as proteolytic enzyme inhibitors and compositions and method of use thereof | SANOFI (FR) | 1999-01-05 | — | — | US | disclosed |
| US-5652254-A | TREATMENT OF DEGENERATIVE DISEASES, RHEUMATOID ARTHRITIS, PSORIASIS, CYSTIC FIBROSIS | SANOFI, S.A. (FR) | 1997-07-29 | — | — | US | disclosed |
| US-5563163-A | TREATMENT OF DEGENERATIVE DISEASES | STERLING WINTHROP, INC. (US) | 1996-10-08 | — | — | US | disclosed |
| US-5488062-A | 2-saccharinylmethyl heterocyclic carboxylates useful as proteolytic enzyme inhibitors and compositions and method of use thereof | STERLING WINTHROP INC. (US) | 1996-01-30 | — | — | US | disclosed |
| US-5376653-A | A protease enzyme inhibitor for treating degenerative diseases , respiratory system disorders, rheumatoid arthritis and pancreatitis | STERLING WINTHROP INC. (US) | 1994-12-27 | — | — | US | disclosed |
| EP-0550111-A1 | 2-Saccharinylmethyl heterocyclic carboxylates useful as proteolytic enzyme inhibitors and pharmaceutical compositions containing them | STERLING WINTHROP INC. (US) | 1993-07-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12583849-B2 | KCNT1 inhibitors and methods of use | KCNT1, SCN1A, KCNT2 | KDM5C 1947/4885FTO 2499/4885KDM4E 2512/4885 |
| US-20150291530-A1 | PROCESS FOR THE PREPARATION OF 2-TRIFLUOROMETHYL ISONICOTINIC ACID AND ESTERS | TAAR1, TAAR5, TSHR | KDM5C 2039/4885FTO 586/4885KDM4E 3684/4885 |
| US-12630533-B2 | Heterocyclic compounds useful as KCNT1 inhibitors | KCNT1, KCNT2, KCNJ2 | KDM5C 2865/4885FTO 3005/4885KDM4E 2324/4885 |
| US-20230295138-A1 | HETEROCYCLYL PYRIDINES AS NOVEL FUNGICIDES | PNPO, CBR3, HPD | KDM5C 616/4885FTO 1227/4885KDM4E 413/4885 |
| US-12552748-B2 | Pyridine (thio)amides as fungicidal compounds | CBR1, CBR3, TH | KDM5C 590/4885FTO 822/4885KDM4E 1771/4885 |
| US-20260085073-A1 | PYRAZOLYLCARBOXAMIDE COMPOUNDS AND THEIR USE IN THERAPY | MALT1, BCL6, BCL3 | KDM5C 2339/4885FTO 3638/4885KDM4E 2636/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.