Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4352375 | 0.82 | HDAC1 (0.50) | HDAC1HDAC6ALDH1A1HSD17B10POLB | |
| SCHEMBL574486 | 0.82 | LMNA (0.61) | HDAC1HDAC6ALDH1A1LMNAPKM | |
| SCHEMBL2882035 | 0.81 | HDAC1 (0.48) | HDAC1HDAC6CYP4F2CYP4A11PPARA | |
| SCHEMBL5034528 | 0.74 | KMT2A (0.53) | CYP4F2CYP4A11ALDH1A1HPGDTDP1 | |
| SCHEMBL5933504 | 0.73 | ALDH1A1 (0.58) | HDAC1HDAC6ALDH1A1HPGDPOLB | |
| SCHEMBL11142759 | 0.73 | LMNA (0.64) | HDAC1HDAC6ALDH1A1HPGDHSD17B10 | |
| SCHEMBL595605 | 0.72 | KMT2A (0.57) | HDAC1HDAC6ALDH1A1HPGDHSD17B10 | |
| SCHEMBL2310278 | 0.72 | RCE1 (0.54) | HDAC1HDAC6TDP1 | |
| SCHEMBL7228409 | 0.72 | MEN1 (0.61) | HDAC1HDAC6ALDH1A1TDP1LMNA | |
| SCHEMBL766565 | 0.72 | L3MBTL1 (0.58) | HDAC1HDAC6ALDH1A1TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1916239-A1 | PYRIDONE COMPOUND | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2008-04-30 | — | — | EP | disclosed |