SCHEMBL5032536

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5035047	0.93	HSD11B1 (0.40)	EPHX2SCD5HPGDPOLBKCNK3
	SCHEMBL5032603	0.90	LIPE (0.41)	EPHX2SCD5HPGDPDK2KCNK3
	SCHEMBL5032557	0.84	PDK2 (0.39)	PDK2ALDH1A1SCN9AKMT2AHSD11B1
	SCHEMBL5032568	0.84	PDK2 (0.39)	PDK2ALDH1A1SCN9AKMT2AHSD11B1
	SCHEMBL5034736	0.83	HSD11B1 (0.45)	SCD5HPGDPOLBKCNK3TRPC3
	SCHEMBL5038957	0.82	LDHA (0.39)	HPGDRAB9AKMT2A
	SCHEMBL5032560	0.81	HSD11B1 (0.49)	HPGDPOLBTRPC3TRPC6NPC1
	SCHEMBL5035020	0.80	NPC1 (0.39)	EPHX2HPGDTRPC3TRPC6NPC1
	SCHEMBL5032604	0.78	TRPC3 (0.42)	HPGDPOLBTRPC3TRPC6NPC1
	SCHEMBL5035140	0.78	HSD11B1 (0.41)	HPGDPOLBTRPC3TRPC6NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.