Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 12/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 11/20 | 0.47 |
| ▸ | PDE4A | P27815 | 8/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 8/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6456302 | 0.88 | PDE4B (0.47) | PDE4DPDE4BPDE4APDE4CABCB11 | |
| SCHEMBL4429839 | 0.87 | PDE4B (0.45) | PDE4DPDE4BPDE4APDE4CABCB11 | |
| SCHEMBL18374066 | 0.80 | RIPK1 (0.42) | PDE4DPDE4BPDE4APDE4CFAAH | |
| SCHEMBL20207588 | 0.78 | RIPK1 (0.43) | PDE4DPDE4BPDE4APDE4CFAAH | |
| SCHEMBL30735868 | 0.77 | PDE4B (0.42) | PDE4DPDE4BPDE4APDE4CABCB11 | |
| SCHEMBL4594035 | 0.77 | PDE4B (0.45) | PDE4DPDE4BPDE4APDE4CABCB11 | |
| SCHEMBL2518447 | 0.76 | PDE4D (0.66) | PDE4DPDE4BPDE4APDE4CABCB11 | |
| SCHEMBL5115860 | 0.75 | CXCR5 (0.43) | PDE4D | |
| SCHEMBL2658234 | 0.75 | FAAH (0.47) | FAAHCNR1CNR2 | |
| SCHEMBL20207066 | 0.75 | RIPK1 (0.40) | PDE4DPDE4BPDE4APDE4CFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117943-A1 | 7-(3',4'-DIALKOXYPHENYL)-[1,2,4]-TRIAZOLO[1,5-A]PYRIMIDINE COMPOUNDS, PROCESS FOR PREPARING THEREOF, AND PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING ASTHMA, CHRONIC OBSTRUCTIVE PULMONARY DISEASE, ARTHRITIS, ATOPIC DERMATITIS, TUMOR AND DEGENERATIVE BRAIN DISEASES COMPRISING THE SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-10-02 | — | — | WO | disclosed |