Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR5 | P32302 | 1/20 | 0.43 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 2/20 | 0.38 |
| ▸ | ACACA | Q13085 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31533374 | 0.82 | PARP15 (0.41) | CXCR5PARP15PARP10PARP2NFKB1 | |
| SCHEMBL4516687 | 0.76 | MAOB (0.55) | PARP15PARP10PARP2THRBNFKB1 | |
| SCHEMBL20207588 | 0.76 | RIPK1 (0.43) | CXCR5PARP15PARP10PARP2KDM4E | |
| SCHEMBL5033170 | 0.75 | PDE4D (0.47) | PDE4D | |
| SCHEMBL18374066 | 0.75 | RIPK1 (0.42) | PARP15PARP10PARP2KDM4EALDH1A1 | |
| SCHEMBL126718 | 0.74 | PARP15 (0.36) | CXCR5PARP15PARP10PARP2NFKB1 | |
| SCHEMBL20342786 | 0.73 | CA1 (0.52) | THRBDRD2KDM4EALDH1A1LMNA | |
| SCHEMBL716744 | 0.73 | MAOB (0.55) | PARP15PARP10PARP2ACACBACACA | |
| SCHEMBL20207066 | 0.72 | RIPK1 (0.40) | CXCR5PARP15PARP10PARP2NFKB1 | |
| SCHEMBL3398683 | 0.70 | THRA (0.45) | CXCR5PARP15PARP10PARP2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7375103-B2 | Optically active pyridine derivative and a medicament containing the same | BAYER HEALTHCARE AG (DE) | 2008-05-20 | — | — | US | disclosed |
| US-20050215547-A1 | Optically active pyridine derivative and a medicament containing the same | BAYER HEALTHCARE AG (DE) | 2005-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050215547-A1 | Optically active pyridine derivative and a medicament containing the same | IL1B, NFKBIA, IL1A | CXCR5 906/4885PARP15 1357/4885PARP10 1280/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.