Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10853381 | 0.80 | CTDSP1 (0.44) | CTDSP1MEN1KMT2AALDH1A1POLB | |
| SCHEMBL5821792 | 0.76 | SMN1; SMN2 (0.42) | CTDSP1MEN1KMT2AALDH1A1POLB | |
| SCHEMBL29221819 | 0.76 | HSP90AA1 (0.53) | MEN1KMT2AALDH1A1L3MBTL1MAPT | |
| SCHEMBL5123738 | 0.75 | ALDH1A1 (0.77) | CTDSP1MEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL3360546 | 0.72 | PTPN1 (0.43) | MEN1KMT2AALDH1A1POLBL3MBTL1 | |
| SCHEMBL1134867 | 0.71 | TSHR (0.60) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL11611701 | 0.71 | OPRM1 (0.58) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL9365608 | 0.70 | ALDH1A1 (0.57) | MEN1KMT2AALDH1A1POLBL3MBTL1 | |
| SCHEMBL9547589 | 0.69 | CES2 (0.44) | MEN1KMT2AALDH1A1POLBL3MBTL1 | |
| SCHEMBL29221790 | 0.69 | ALDH1A1 (0.62) | MEN1KMT2AALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1919465-A2 | GSK-3 INHIBITORS | Neuropharma S.A. (ES) | 2008-05-14 | — | — | EP | disclosed |
| WO-2007017145-A2 | GSK-3 INHIBITORS | NEUROPHARMA, S.A. (ES) | 2007-02-15 | — | — | WO | disclosed |