Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | HCAR3 | P49019 | 11/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7588376 | 1.00 | TDP1 (0.44) | TDP1HCAR3HPGDHCAR2RAB9A | |
| SCHEMBL5827487 | 0.81 | KDM4E (0.42) | RAB9ANPC1MEN1KMT2AKDM4E | |
| SCHEMBL7173837 | 0.81 | KDM4E (0.42) | RAB9ANPC1MEN1KMT2AKDM4E | |
| SCHEMBL5828526 | 0.73 | HCAR3 (0.50) | HCAR3HPGDHCAR2 | |
| SCHEMBL5828225 | 0.73 | HCAR3 (0.60) | HCAR3HPGDHCAR2 | |
| SCHEMBL14478264 | 0.71 | NPC1 (0.44) | TDP1HCAR3HPGDHCAR2RAB9A | |
| SCHEMBL503399 | 0.68 | NPC1 (0.41) | TDP1HCAR3HPGDRAB9ANPC1 | |
| SCHEMBL11562828 | 0.67 | MAPT (0.58) | TDP1HPGDRAB9ANPC1MEN1 | |
| SCHEMBL11562276 | 0.65 | TDP1 (0.47) | TDP1HPGDRAB9ANPC1MEN1 | |
| SCHEMBL2401376 | 0.65 | MYC (0.51) | TDP1HCAR3HPGDRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7015331-B2 | Non-proteinogenic L-amino acids | Consortium für elektrochemische Industrie GmbH (DE) | 2006-03-21 | — | — | US | claimed |
| US-20050222426-A1 | Non-proteinogenic L-amino acids | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH | 2005-10-06 | — | — | US | claimed |
| US-20040197879-A1 | Process for producing non-proteinogenic L-amino acids by fermentation | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH | 2004-10-07 | — | — | US | claimed |
| US-20020039767-A1 | Process for producing non-proteinogenic L-amino acids by fermentation | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH | 2002-04-04 | — | — | US | claimed |
| EP-1191106-A1 | Verfahren zur fermentativen Herstellung von nicht-proteinogenen L-Aminosäuren | Consortium für elektrochemische Industrie GmbH (DE) | 2002-03-27 | — | — | EP | claimed |
| US-8445678-B2 | 2-quinoxalinol salen compounds and uses thereof | AUBURN UNIVERSITY (US) | 2013-05-21 | — | — | US | disclosed |
| US-20120028362-A1 | 2-QUINOXALINOL SALEN COMPOUNDS AND USES THEREOF | AUBURN UNIVERSITY (US) | 2012-02-02 | — | — | US | disclosed |
| US-20090286968-A1 | 2-Quinoxalinol Salen Compounds and Uses Thereof | AUBURN UNIVERSITY (US) | 2009-11-19 | — | — | US | disclosed |
| US-7015331-B2 | Non-proteinogenic L-amino acids | Consortium für elektrochemische Industrie GmbH (DE) | 2006-03-21 | — | — | US | disclosed |
| US-20050222426-A1 | Non-proteinogenic L-amino acids | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH | 2005-10-06 | — | — | US | disclosed |
| US-6939967-B2 | Non-proteinogenic L-amino acids | Consortium für elektrochemische Industrie GmbH (DE) | 2005-09-06 | — | — | US | disclosed |
| US-20040197879-A1 | Process for producing non-proteinogenic L-amino acids by fermentation | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH | 2004-10-07 | — | — | US | disclosed |
| US-6756216-B2 | BATCH PROCESSING USING NUCLEOPHILIC COMPOUND | Consortium für elektrochemische Industrie GmbH (DE) | 2004-06-29 | — | — | US | disclosed |
| EP-1191106-B1 | Process for the fermentative preparation of non-proteinogenic L-amino acids | CONSORTIUM ELEKTROCHEM IND (DE) | 2004-04-28 | — | — | EP | disclosed |
| US-6579705-B2 | Generating preferential amino acid sequences; obtain adjusted amino acid, incubate with enzyme, recover amino acid | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 2003-06-17 | — | — | US | disclosed |
| US-20020177196-A1 | Process for preparing non-proteinogenic L-amino acids | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH | 2002-11-28 | — | — | US | disclosed |
| EP-1247869-A1 | Process for the production of non-proteinogenic amino acids | Consortium für elektrochemische Industrie GmbH (DE) | 2002-10-09 | — | — | EP | disclosed |
| US-20020039767-A1 | Process for producing non-proteinogenic L-amino acids by fermentation | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH | 2002-04-04 | — | — | US | disclosed |
| EP-1191106-A1 | Verfahren zur fermentativen Herstellung von nicht-proteinogenen L-Aminosäuren | Consortium für elektrochemische Industrie GmbH (DE) | 2002-03-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050222426-A1 | Non-proteinogenic L-amino acids | BCAT2, BCAT1, CBS | TDP1 4207/4885HCAR3 3857/4885HPGD 1041/4885 |
| US-20020039767-A1 | Process for producing non-proteinogenic L-amino acids by fermentation | CBS, BCAT2, BCAT1 | TDP1 4425/4885HCAR3 4197/4885HPGD 979/4885 |
| US-20090286968-A1 | 2-Quinoxalinol Salen Compounds and Uses Thereof | NQO1, NQO2, SQOR | TDP1 2894/4885HCAR3 2250/4885HPGD 143/4885 |
| US-20120028362-A1 | 2-QUINOXALINOL SALEN COMPOUNDS AND USES THEREOF | NQO1, NQO2, SQOR | TDP1 2894/4885HCAR3 2250/4885HPGD 143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.