Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | CASP3 | P42574 | 3/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.44 |
| ▸ | VSIR | Q9H7M9 | 3/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18583160 | 0.79 | SMN1; SMN2 (0.68) | SMN1; SMN2KDM4ECASP3SENP7SENP6 | |
| SCHEMBL2244889 | 0.77 | BCHE (0.60) | SMN1; SMN2KDM4ECASP3SENP7SENP6 | |
| SCHEMBL5035378 | 0.77 | BCHE (0.60) | SMN1; SMN2KDM4ECASP3SENP7SENP6 | |
| SCHEMBL14215998 | 0.76 | KDM4E (0.44) | SMN1; SMN2KDM4ECASP3SENP7SENP6 | |
| SCHEMBL2247274 | 0.75 | KDM4E (0.59) | SMN1; SMN2KDM4ECASP3SENP7SENP6 | |
| SCHEMBL22304347 | 0.74 | RAB9A (0.60) | SMN1; SMN2KDM4ECASP3SENP7SENP6 | |
| SCHEMBL9018554 | 0.73 | NPC1 (0.68) | SMN1; SMN2KDM4ECASP3SENP7SENP6 | |
| SCHEMBL23079706 | 0.72 | NPC1 (0.59) | SMN1; SMN2KDM4ECASP3SENP7SENP6 | |
| SCHEMBL13067698 | 0.72 | NPC1 (0.59) | SMN1; SMN2KDM4ECASP3SENP7SENP6 | |
| SCHEMBL15413714 | 0.72 | NPC1 (0.66) | SMN1; SMN2KDM4ECASP3SENP7SENP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080124807-A1 | Protein tagging reagents | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2008-05-29 | — | — | US | disclosed |
| US-20080124807-A1 | Protein tagging reagents | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2008-05-29 | — | — | US | disclosed |
| US-20080124807-A1 | Protein tagging reagents | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2008-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080124807-A1 | Protein tagging reagents | TH, TPH1, TPH2 | SMN1; SMN2 4101/4885KDM4E 904/4885CASP3 4351/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.