SCHEMBL5034622

SCHEMBL5034622

C=C(C)c1ccccc1-c1ccccc1CC

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CSNK2A2 P19784 1/20 0.39
CSNK2B P67870 1/20 0.39
CSNK2A1 P68400 1/20 0.39
CSNK2A3 Q8NEV1 1/20 0.39
GABRA1 P14867 2/20 0.39
GABRB2 P47870 2/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
ALDH1A1 P00352 2/20 0.38
CLCN2 P51788 1/20 0.37
CYP2D6 P10635 1/20 0.36
FOLH1 Q04609 1/20 0.36
PDK2 Q15119 1/20 0.35
SLC9A1 P19634 1/20 0.35
TSHR P16473 1/20 0.34
LMNA P02545 1/20 0.34
SHBG P04278 1/20 0.34
KCNA5 P22460 2/20 0.34
DHFR P00374 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL721894 0.84 GABRA1 (0.44) GABRA1GABRB2ALDH1A1CLCN2FOLH1
SCHEMBL29396009 0.84 GABRA1 (0.44) GABRA1GABRB2ALDH1A1CLCN2FOLH1
SCHEMBL1208344 0.83 ALDH1A1 (0.39) MEN1KMT2AALDH1A1CLCN2LMNA
SCHEMBL8614505 0.82 HSD17B1 (0.43) CSNK2A2CSNK2BCSNK2A1CSNK2A3GABRA1
SCHEMBL8144422 0.80 CLCN2 (0.37) CSNK2A2CSNK2BCSNK2A1CSNK2A3GABRA1
Dimethylamine SCHEMBL27844896 0.78 CLCN2 (0.41) GABRA1GABRB2ALDH1A1CLCN2TSHR
SCHEMBL7843765 0.78 FOLH1 (0.56) MEN1KMT2AALDH1A1CLCN2FOLH1
SCHEMBL198461 0.78 CSNK2A2 (0.52) CSNK2A2CSNK2BCSNK2A1CSNK2A3GABRA1
SCHEMBL528444 0.77 BCAT2 (0.55) CSNK2A2CSNK2BCSNK2A1CSNK2A3MEN1
SCHEMBL28116443 0.77 PDK2 (0.44) CSNK2A2CSNK2BCSNK2A1CSNK2A3GABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7402645-B2 Soluble polyfunctional vinyl aromatic polymer and method of producing the same NIPPON STEEL CHEMICAL CO., LTD. (JP) 2008-07-22 US disclosed
US-20070155923-A1 Soluble polyfunctional vinyl aromatic polymer and method of producing the same NIPPON STEEL CHEMICAL CO., LTD. (JP) 2007-07-05 US disclosed
EP-0150908-B1 Use of Curable impregnant compositions for impregnating electrical appliances NIPPON PETROCHEMICALS CO LTD (JP) 1998-04-15 EP disclosed
US-4670348-A Electrical appliance impregnated with a curable impregnant composition NIPPON PETROCHEMICALS CO., LTD. (JP) 1987-06-02 US disclosed
EP-0150908-A1 Use of Curable impregnant compositions for impregnating electrical appliances NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1985-08-07 EP disclosed