Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 2/20 | 0.45 |
| ▸ | CNR1 | P21554 | 17/20 | 0.39 |
| ▸ | CNR2 | P34972 | 11/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5035268 | 0.91 | LIPE (0.47) | LIPECNR1CNR2 | |
| SCHEMBL5032559 | 0.84 | CNR1 (0.48) | CNR1CNR2 | |
| SCHEMBL5034926 | 0.83 | LIPE (0.46) | LIPECNR1CNR2 | |
| SCHEMBL5039110 | 0.82 | CYP3A4 (0.42) | — | |
| SCHEMBL5036060 | 0.81 | CYP3A4 (0.43) | — | |
| SCHEMBL5041330 | 0.79 | CYP3A4 (0.44) | CNR1 | |
| SCHEMBL5034899 | 0.78 | NLRP3 (0.38) | — | |
| SCHEMBL5039137 | 0.77 | POLB (0.40) | LIPE | |
| SCHEMBL5032567 | 0.77 | CYP3A4 (0.49) | CNR1CNR2 | |
| SCHEMBL5032552 | 0.76 | NPC1 (0.45) | CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1694673-B1 | THIAZOLE DERIVATES | HOFFMANN LA ROCHE (CH) | 2008-01-16 | — | — | EP | claimed |