SCHEMBL5035404

SCHEMBL5035404

COc1ccc2[nH]c3c(C)nccc3c2c1

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 7/20 0.78
DYRK1A Q13627 6/20 0.78
KDM4E B2RXH2 4/20 0.78
ALDH1A1 P00352 3/20 0.78
HSD17B10 Q99714 3/20 0.78
ACHE P22303 3/20 0.78
CYP1A2 P05177 2/20 0.78
CYP3A4 P08684 2/20 0.78
CYP2D6 P10635 2/20 0.78
HPGD P15428 2/20 0.78
HTR2C P28335 2/20 0.78
CCNB2 O95067 2/20 0.78
CDK1 P06493 2/20 0.78
CCNB1 P14635 2/20 0.78
CCNA2 P20248 2/20 0.78
CDK2 P24941 2/20 0.78
CCNA1 P78396 2/20 0.78
CDK5 Q00535 2/20 0.78
CDK5R1 Q15078 2/20 0.78
CCNB3 Q8WWL7 2/20 0.78

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6123447 0.90 MAOA (0.68) MAOADYRK1AKDM4EALDH1A1HSD17B10
Harmine SCHEMBL30510974 0.88 MAOA (1.00) MAOADYRK1AKDM4EALDH1A1HSD17B10
Harmine SCHEMBL29440552 0.88 MAOA (1.00) MAOADYRK1AKDM4EALDH1A1HSD17B10
Harmine SCHEMBL29941920 0.88 MAOA (1.00) MAOADYRK1AKDM4EALDH1A1HSD17B10
Harmine SCHEMBL9481427 0.88 MAOA (1.00) MAOADYRK1AKDM4EALDH1A1HSD17B10
Harmine SCHEMBL292955 0.88 MAOA (1.00) MAOADYRK1AKDM4EALDH1A1HSD17B10
Harmine SCHEMBL1469013 0.87 KLK7 (1.00) MAOADYRK1AKDM4EALDH1A1HSD17B10
Harmine SCHEMBL30726913 0.87 KLK7 (1.00) MAOADYRK1AKDM4EALDH1A1HSD17B10
Harmine SCHEMBL16099771 0.87 MAOA (0.97) MAOADYRK1AKDM4EALDH1A1HSD17B10
Harmine SCHEMBL31500130 0.85 KLK7 (0.97) MAOADYRK1AKDM4EALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117705184-A Detection method for chemical components of anemone-resistant tung tree 中国热带农业科学院热带作物品种资源研究所 2024-03-15 CN claimed
US-20250171749-A1 GENETICALLY MODIFIED ORGANISMS FOR PRODUCING PSYCHOTROPIC ALKALOIDS Empyrean Neuroscience, Inc. 2025-05-29 US disclosed
EP-4457336-A2 GENETICALLY MODIFIED ORGANISMS FOR PRODUCING PSYCHOTROPIC ALKALOIDS Empyrean Neuroscience, Inc. (US) 2024-11-06 EP disclosed
CN-118787686-A Diabetes treating medicine and its prepn 杨志岐 2024-10-18 CN disclosed
US-12104179-B2 Genetically modified organisms for producing psychotropic alkaloids Empyrean Neuroscience, Inc. (US) 2024-10-01 US disclosed
CN-116751197-B Carbolin alkaloid or pharmaceutically acceptable salt thereof, preparation method and application thereof, and carbolin alkaloid pharmaceutical composition and application thereof 中国科学院昆明植物研究所 2024-04-12 CN disclosed
US-20240101976-A1 GENETICALLY MODIFIED ORGANISMS FOR PRODUCING PSYCHOTROPIC ALKALOIDS Empyrean Neuroscience, Inc. 2024-03-28 US disclosed
CN-117705184-A Detection method for chemical components of anemone-resistant tung tree 中国热带农业科学院热带作物品种资源研究所 2024-03-15 CN disclosed
US-20240009332-A1 COMPOSITE EMBOLIZATION BEADS TRANSLATIONAL AND FUNDAMENTAL TECHNOLOGIES INSTITUTE LLC 2024-01-11 US disclosed
US-20230398166-A1 METHOD FOR EXTRACTING A FULL SPECTRUM OF HYDROPHILIC COMPOUNDS FROM BIOMASS TUDELA JERRED (US) 2023-12-14 US disclosed
US-7429397-B2 Herbal formulation as memory enhancer in Alzheimer condition COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2008-09-30 US disclosed
EP-1567177-B1 MUCUNA PRURIENS AND EXTRACTS THEREOF FOR THE TREATMENT OF NEUROLOGICAL DISEASES PHYTRIX AG (DE) 2008-04-23 EP disclosed
US-20070042054-A1 FUNCTIONAL APHRODISIAC ROLLED HERBAL BIDIS AND CIGARETTES COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH 2007-02-22 US disclosed
WO-2006111830-A2 FUNCTIONAL APHRODISIAC ROLLED HERBAL BIDIS AND CIGARETTES COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2006-10-26 WO disclosed
US-20060165822-A1 Pharmaceutical compositions and uses comprising mucuna pruriens seed powder and extracts thereof in the treatment of neurological diseases PHYTRIX AG (DE) 2006-07-27 US disclosed
US-20060141068-A1 Herbal formulation as memory enhancer in alzheimer condition COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH 2006-06-29 US disclosed
WO-2006067796-A1 HERBAL FORMULATION AS MEMORY ENHACHER IN ALZHEIMER CONDITION COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2006-06-29 WO disclosed
EP-1567177-A2 MUCUNA PRURIENS AND EXTRACTS THEREOF FOR THE TREATMENT OF NEUROLOGICAL DISEASES Phytrix AG (DE) 2005-08-31 EP disclosed
WO-2004039385-A2 MUCUNA PRURIENS AND EXTRACTS THEREOF FOR THE TREATMENT OF NEUROLOGICAL DISEASES PHYTRIX AG (DE) 2004-05-13 WO disclosed
US-20010056085-A1 Methods of using vesicant drug formulations RAMU AVNER (US) 2001-12-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010056085-A1 Methods of using vesicant drug formulations UGT1A1, SLC47A1, UGT1A10 MAOA 1710/4885DYRK1A 3504/4885KDM4E 2544/4885
US-20250171749-A1 GENETICALLY MODIFIED ORGANISMS FOR PRODUCING PSYCHOTROPIC ALKALOIDS PNMT, INMT, AANAT MAOA 5/4885DYRK1A 569/4885KDM4E 754/4885
US-20240101976-A1 GENETICALLY MODIFIED ORGANISMS FOR PRODUCING PSYCHOTROPIC ALKALOIDS PNMT, INMT, AANAT MAOA 5/4885DYRK1A 569/4885KDM4E 754/4885
US-12104179-B2 Genetically modified organisms for producing psychotropic alkaloids PNMT, INMT, AANAT MAOA 5/4885DYRK1A 569/4885KDM4E 754/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.