SCHEMBL503629

SCHEMBL503629

OCCOCCNN1CCOCC1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.44
GAA P10253 1/20 0.44
KDM1A O60341 1/20 0.38
TSHR P16473 2/20 0.37
MAPK1 P28482 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
ALDH1A1 P00352 2/20 0.34
KDM4E B2RXH2 1/20 0.34
CA12 O43570 2/20 0.33
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA9 Q16790 2/20 0.33
HTT P42858 1/20 0.33
GLA P06280 1/20 0.33
TDP1 Q9NUW8 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
MERTK Q12866 1/20 0.31
LIPE Q05469 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6505659 0.80 ALDH1A1 (0.41) POLBGAAKDM1AL3MBTL1ALDH1A1
SCHEMBL13451264 0.75 TDP1 (0.47) GAAKDM1AMAPK1MEN1KMT2A
Di(Hydroxyethyl)Ether SCHEMBL2066155 0.72 TSHR (0.62) POLBGAATSHRMAPK1L3MBTL1
SCHEMBL503668 0.71 KDM4E (0.57) POLBGAATSHRL3MBTL1ALDH1A1
SCHEMBL28477691 0.70 POLB (0.41) POLBGAAL3MBTL1ALDH1A1KDM4E
Di(Hydroxyethyl)Ether SCHEMBL5009910 0.70 TSHR (0.67) POLBGAATSHRMAPK1L3MBTL1
SCHEMBL525957 0.69 KDM4E (0.55) POLBGAATSHRL3MBTL1MEN1
SCHEMBL10603635 0.69 POLB (0.46) POLBGAATSHRMAPK1L3MBTL1
SCHEMBL22840863 0.69 KDM4E (0.55) POLBGAATSHRL3MBTL1MEN1
SCHEMBL21169723 0.69 KDM1A (0.41) KDM1AALDH1A1CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6767399-B2 FLOWABILITY AND HIGH EARLY STRENGTH THE EUCLID CHEMICAL COMPANY 2004-07-27 US claimed
US-20030167973-A1 Admixture for producing cementitious compositions having good fluidity and high early compressive strength BORAL MATERIAL TECHNOLOGIES, INC. 2003-09-11 US claimed
US-5928672-A REACTION PRODUCT OF A BORIC ACID COMPOUND AND A PLURALITY OF CYCLIC AMINES IN WATER, WHEREIN AT LEAST ONE OF THE CYCLIC AMINES IS MORPHOLINEAMINODIGLYCOL; HEAT STABILITY; FERTILIZERS HAMMONS BARRY D (US) 1999-07-27 US claimed
US-11518749-B2 Method for the continuous separation by distillation of mixtures that contain morpholine (MO), monoaminodiglycol (ADG), ammonia, water and methoxyethanol (MOE) BASF SE (DE) 2022-12-06 US disclosed
EP-3755691-B1 METHOD FOR THE CONTINUOUS DESTILLATIVE SEPARATION OF MIXTURES COMPRISING MORPHOLINE (MO), MONOAMINODIGLYCOL (ADG), AMMONIA, WATER AND METHOXYETHANOL (MOE) BASF SE (DE) 2022-04-06 EP disclosed
EP-3755691-A1 METHOD FOR THE CONTINUOUS SEPARATION BY DISTILLATION OF MIXTURES THAT CONTAIN MORPHOLINE (MO), MONOAMINODIGLYCOL (ADG), AMMONIA, WATER AND METHOXYETHANOL (MOE) BASF SE (DE) 2020-12-30 EP disclosed
US-20200392093-A1 METHOD FOR THE CONTINUOUS SEPARATION BY DISTILLATION OF MIXTURES THAT CONTAIN MORPHOLINE (MO), MONOAMINODIGLYCOL (ADG), AMMONIA, WATER AND METHOXYETHANOL (MOE) BASF SE (DE) 2020-12-17 US disclosed
CN-111741949-A Method for the continuous separation by distillation of a mixture comprising Morpholine (MO), monoaminodiglycol (ADG), ammonia, water and Methoxyethanol (MOE) 巴斯夫欧洲公司 2020-10-02 CN disclosed
WO-2019162121-A1 METHOD FOR THE CONTINUOUS SEPARATION BY DISTILLATION OF MIXTURES THAT CONTAIN MORPHOLINE (MO), MONOAMINODIGLYCOL (ADG), AMMONIA, WATER AND METHOXYETHANOL (MOE) BASF SE (DE) 2019-08-29 WO disclosed
US-8293075-B2 Method for the continuous separation by distillation of mixtures that contain morphonline (MO), monoaminodiglycol (ADG), ammonia and water by means of distillation BASF SE (DE) 2012-10-23 US disclosed
US-8246793-B2 Method for the continuous separation of mixtures comprising morpholine (MO), monoaminodiglycol (ADG), ammonia and water by means of distillation BASF SE (DE) 2012-08-21 US disclosed
US-8197646-B2 Processes for continuous fractional distillation of mixtures comprising morpholine, monoaminodiglycol, ammonia and water BASF SE (DE) 2012-06-12 US disclosed
US-20120024689-A1 METHOD FOR THE CONTINUOUS SEPARATION OF MIXTURES COMPRISING MORPHONLINE (MO), MONOAMINODIGLYCOL (ADG), AMMONIA AND WATER BY MEANS OF DISTILLATION BASF SE (DE) 2012-02-02 US disclosed
US-20100084257-A1 METHOD FOR THE CONTINUOUS SEPARATION OF MIXTURES COMPRISING MORPHOLINE (MO), MONOAMINODIGLYCOL (ADG), AMMONIA AND WATER BY MEANS OF DISTILLATION BASF SE (DE) 2010-04-08 US disclosed
US-20100084258-A1 METHOD FOR THE CONTINUOUS SEPARATION OF MIXTURES COMPRISING MORPHOLINE (MO), MONOAMINODIGLYCOL (ADG), AMMONIA AND WATER BY MEANS OF DISTILLATION BASF SE (DE) 2010-04-08 US disclosed
US-6767399-B2 FLOWABILITY AND HIGH EARLY STRENGTH THE EUCLID CHEMICAL COMPANY 2004-07-27 US disclosed
US-20030167973-A1 Admixture for producing cementitious compositions having good fluidity and high early compressive strength BORAL MATERIAL TECHNOLOGIES, INC. 2003-09-11 US disclosed
US-5928672-A REACTION PRODUCT OF A BORIC ACID COMPOUND AND A PLURALITY OF CYCLIC AMINES IN WATER, WHEREIN AT LEAST ONE OF THE CYCLIC AMINES IS MORPHOLINEAMINODIGLYCOL; HEAT STABILITY; FERTILIZERS HAMMONS BARRY D (US) 1999-07-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200392093-A1 METHOD FOR THE CONTINUOUS SEPARATION BY DISTILLATION OF MIXTURES THAT CONTAIN MORPHOLINE (MO), MONOAMINODIGLYCOL (ADG), AMMONIA, WATER AND METHOXYETHANOL (MOE) MYH10, MGLL, AGL POLB 686/4885GAA 624/4885KDM1A 2321/4885
US-20100084257-A1 METHOD FOR THE CONTINUOUS SEPARATION OF MIXTURES COMPRISING MORPHOLINE (MO), MONOAMINODIGLYCOL (ADG), AMMONIA AND WATER BY MEANS OF DISTILLATION MYH10, AGL, ODC1 POLB 1013/4885GAA 460/4885KDM1A 1912/4885
US-11518749-B2 Method for the continuous separation by distillation of mixtures that contain morpholine (MO), monoaminodiglycol (ADG), ammonia, water and methoxyethanol (MOE) MYH10, MGLL, AGL POLB 686/4885GAA 624/4885KDM1A 2321/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.