Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | FAAH | O00519 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.49 |
| ▸ | CA5A | P35218 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CNR1 | P21554 | 2/20 | 0.48 |
| ▸ | CNR2 | P34972 | 2/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19450068 | 0.80 | POLB (0.51) | POLB | |
| SCHEMBL5034461 | 0.79 | FAAH (0.46) | EPHX2FAAH | |
| SCHEMBL5043991 | 0.79 | ALDH1A1 (0.47) | EPHX2MEN1KMT2ACYP3A4CYP2C19 | |
| SCHEMBL5037670 | 0.76 | NOD1 (0.47) | EPHX2MEN1KMT2AFAAHCNR1 | |
| SCHEMBL14186683 | 0.76 | NOD1 (0.47) | EPHX2MEN1KMT2AFAAHCNR1 | |
| SCHEMBL27703735 | 0.76 | MEN1 (0.83) | GAAEPHX2MEN1KMT2AFAAH | |
| SCHEMBL4401015 | 0.76 | EPHX2 (0.87) | GAAEPHX2MEN1KMT2AFAAH | |
| SCHEMBL2942358 | 0.75 | MEN1 (0.96) | GAAEPHX2MEN1KMT2AFAAH | |
| SCHEMBL1516109 | 0.74 | EPHX2 (0.97) | GAAEPHX2MEN1KMT2AFAAH | |
| SCHEMBL10963930 | 0.74 | GAA (0.77) | GAAEPHX2MEN1KMT2ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1339669-B1 | N-ALKYLATED GABA COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | UCB PHARMA SA (BE) | 2008-06-04 | — | — | EP | disclosed |
| US-7112612-B2 | N-alkylated GABA compounds, processes for their preparation and their use as medicaments | UCB S.A. (BE) | 2006-09-26 | — | — | US | disclosed |