SCHEMBL503915

SCHEMBL503915

CCCCCCCCCCCCC1(COCC2(CCCCCCCCCCCC)CCCO2)CCCO1

nearest known ligand 0.44

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SIRT2 Q8IXJ6 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7878187 1.00 SIRT2 (0.44) SIRT2
SCHEMBL7882697 1.00 SIRT2 (0.44) SIRT2
SCHEMBL503738 1.00 SIRT2 (0.44) SIRT2
SCHEMBL503940 1.00 SIRT2 (0.44) SIRT2
SCHEMBL503987 0.93 SIRT2 (0.36) SIRT2
SCHEMBL5140463 0.87 SIRT2 (0.46) SIRT2
SCHEMBL503714 0.85
SCHEMBL8791545 0.85 SIRT2 (0.44) SIRT2
SCHEMBL16834542 0.83 ALDH1A1 (0.40) SIRT2
SCHEMBL10866327 0.82 CETP (0.39) SIRT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240109996-A1 POLYMER TERMINATED WITH POLYAROMATIC HYDROCARBON MIZUHO BANK, LTD., AS ADMINISTRATIVE AGENT 2024-04-04 US claimed
US-6515087-B2 Continuous anionic polymerization of conjugated diolefin monomers; excellent interaction with fillers; catalysts containing organolithium compound and a secondary amine THE GOODYEAR TIRE & RUBBER COMPANY 2003-02-04 US claimed
US-20020120082-A1 Synthesis of elastomers having low hysteresis GOODYEAR TIRE & RUBBER COMPANY, THE 2002-08-29 US claimed
US-20260035495-A1 FUNCTIONAL COPOLYMERS AND METHODS OF PREPARATION THEREOF Kraton Corporation (US) 2026-02-05 US disclosed
US-12534558-B2 Polymer terminated with polyaromatic hydrocarbon G-3 CHICKADEE PURCHASER, LLC (US) 2026-01-27 US disclosed
US-20250109229-A1 METHOD OF PRODUCING FUNCTIONALIZED POLYMERS, RUBBER COMPOSITION, AND PNEUMATIC TIRE MIZUHO BANK, LTD., AS ADMINISTRATIVE AGENT 2025-04-03 US disclosed
EP-4530094-A1 METHOD OF PRODUCING FUNCTIONALIZED POLYMERS, RUBBER COMPOSITION, AND PNEUMATIC TIRE The Goodyear Tire & Rubber Company (US) 2025-04-02 EP disclosed
US-12110303-B2 Mixtures of aminosilyl-functionalized styrenes, their preparation and their use in the production of elastomeric copolymers SYNTHOS S.A. (PL) 2024-10-08 US disclosed
US-20240109996-A1 POLYMER TERMINATED WITH POLYAROMATIC HYDROCARBON MIZUHO BANK, LTD., AS ADMINISTRATIVE AGENT 2024-04-04 US disclosed
US-11525049-B2 Polar additive for the synthesis of copolymers of vinylaromatic monomer and conjugated diene monomer having high vinylaromatic and low vinyl contents SYNTHOS S.A. (PL) 2022-12-13 US disclosed
CN-111285950-B Functionalized polymer, rubber composition and pneumatic tire 固特异轮胎和橡胶公司 2022-08-05 CN disclosed
US-6693160-B1 FREE RADICAL COPOLYMERS OF CONJUGATED DIOLEFIN AND NITROGEN HETEROCYCLE FUNCTIONALIZED MONOMERS; LOW HYSTERESIS; FILLER COMPATIBILITY THE GOODYEAR TIRE & RUBBER COMPANY 2004-02-17 US disclosed
US-6670471-B1 Low hysteresis and good compatibility with fillers; reacting a cyclic secondary amine with a vinyl aromatic halide in the presence of a base; alkylamine-functional styrene copolymer with a conjugated diolefin monomer; tires THE GOODYEAR TIRE & RUBBER COMPANY 2003-12-30 US disclosed
US-6664328-B1 Tire with tread comprised of filler and rubbery polymer comprised of repeat units derived from conjugated diolefin monomer and functionalized monomer of specified structural formula; low hysteresis, good compatibility with filler THE GOODYEAR TIRE & RUBBER COMPANY 2003-12-16 US disclosed
US-6630552-B1 Butadiene-styrene copolymers with heterocyclic amine compounds THE GOODYEAR TIRE & RUBBER COMPANY 2003-10-07 US disclosed
US-6627721-B1 Rubbery polymer comprised of comonomers of conjugated diene and styrene substited with N-heterocycle or sulfide; hoses, power transmission belts THE GOODYEAR TIRE & RUBBER COMPANY 2003-09-30 US disclosed
US-6627722-B2 Rubber comprising comonomers of conjugated diolefin and vinyllaromatic compound substituted with N-heterocycle; tire treads GOODYEAR TIRE & RUBBER COMPANY, THE 2003-09-30 US disclosed
US-20030134997-A1 Functionalized elastomers THE GOODYEAR TIRE & RUBBER COMPANY 2003-07-17 US disclosed
US-6515087-B2 Continuous anionic polymerization of conjugated diolefin monomers; excellent interaction with fillers; catalysts containing organolithium compound and a secondary amine THE GOODYEAR TIRE & RUBBER COMPANY 2003-02-04 US disclosed
US-20020120082-A1 Synthesis of elastomers having low hysteresis GOODYEAR TIRE & RUBBER COMPANY, THE 2002-08-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260035495-A1 FUNCTIONAL COPOLYMERS AND METHODS OF PREPARATION THEREOF VCL, FGB, CDH1 SIRT2 4124/4885
US-12110303-B2 Mixtures of aminosilyl-functionalized styrenes, their preparation and their use in the production of elastomeric copolymers ECPAS, ILK, STT3A SIRT2 2647/4885
US-12534558-B2 Polymer terminated with polyaromatic hydrocarbon POT1, TST, TELO2 SIRT2 1227/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.