Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 1/20 | 0.63 |
| ▸ | LTK | P29376 | 1/20 | 0.63 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.63 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.63 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5044397 | 0.78 | NTRK1 (0.61) | NTRK1LTKTYRO3NTRK2CLK4 | |
| SCHEMBL5041289 | 0.78 | CLK4 (1.00) | NTRK1LTKTYRO3NTRK2CLK4 | |
| SCHEMBL5133731 | 0.73 | CLK4 (0.37) | NTRK1LTKTYRO3NTRK2CLK4 | |
| SCHEMBL10252852 | 0.67 | IKBKB (0.41) | NTRK1LTKTYRO3NTRK2CLK4 | |
| SCHEMBL5036336 | 0.64 | — | — | |
| SCHEMBL844706 | 0.62 | NTRK1 (0.43) | NTRK1LTKTYRO3NTRK2CLK4 | |
| SCHEMBL24400862 | 0.62 | HTR1A (0.31) | HTR1AHTR2C | |
| SCHEMBL353890 | 0.61 | SMN1; SMN2 (0.63) | ALDH1A1KDM4ELMNANPC1RAB9A | |
| SCHEMBL3759451 | 0.61 | LMNA (0.65) | NTRK1NTRK2CLK4ALDH1A1KDM4E | |
| SCHEMBL24400857 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1715840-B1 | KERATIN DYEING COMPOSITIONS CONTAINING BICYCLIC FUSED 5-5 HETEROAROMATIC DYES | PROCTER & GAMBLE (US) | 2008-12-03 | — | — | EP | claimed |
| US-20230203057-A1 | FIVE-MEMBERED HETEROAROMATIC IMIDAZOLE COMPOUND AND USE THEREOF | HANGZHOU SCIWIND BIOSCIENCES CO., LTD (CN) | 2023-06-29 | — | — | US | disclosed |
| US-20230203057-A1 | FIVE-MEMBERED HETEROAROMATIC IMIDAZOLE COMPOUND AND USE THEREOF | HANGZHOU SCIWIND BIOSCIENCES CO., LTD (CN) | 2023-06-29 | — | — | US | disclosed |
| US-11542272-B2 | Five-membered heteroaryl-fused imidazole compound and application thereof | HANGZHOU SCIWIND BIOSCIENCES CO., LTD (CN) | 2023-01-03 | — | — | US | disclosed |
| US-20220135588-A1 | Five-Membered Heteroaryl-Fused Imidazole Compound And Application Thereof | HANGZHOU SCIWIND BIOSCIENCES CO., LTD (CN) | 2022-05-05 | — | — | US | disclosed |
| US-20120020920-A1 | 5-5-MEMBERED FUSED HETEROCYCLIC COMPOUND AND USE THEREOF AS HCV POLYMERASE INHIBITOR | JAPAN TOBACCO INC. (JP) | 2012-01-26 | — | — | US | disclosed |
| EP-1715840-B1 | KERATIN DYEING COMPOSITIONS CONTAINING BICYCLIC FUSED 5-5 HETEROAROMATIC DYES | PROCTER & GAMBLE (US) | 2008-12-03 | — | — | EP | disclosed |
| US-7303590-B2 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2007-12-04 | — | — | US | disclosed |
| US-20050193502-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | PROCTER, GAMBLE COMPANY, THE | 2005-09-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120020920-A1 | 5-5-MEMBERED FUSED HETEROCYCLIC COMPOUND AND USE THEREOF AS HCV POLYMERASE INHIBITOR | GTF3C5, ZC3HAV1, POLI | NTRK1 4883/4885LTK 2898/4885TYRO3 4347/4885 |
| US-20220135588-A1 | Five-Membered Heteroaryl-Fused Imidazole Compound And Application Thereof | GLP1R, GIPR, GPR119 | NTRK1 843/4885LTK 1162/4885TYRO3 481/4885 |
| US-20230203057-A1 | FIVE-MEMBERED HETEROAROMATIC IMIDAZOLE COMPOUND AND USE THEREOF | GLP1R, GIPR, GPR119 | NTRK1 1204/4885LTK 1664/4885TYRO3 586/4885 |
| US-11542272-B2 | Five-membered heteroaryl-fused imidazole compound and application thereof | GLP1R, GIPR, GPR119 | NTRK1 843/4885LTK 1162/4885TYRO3 481/4885 |
| US-20050193502-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | KRT18, KLK5, CKMT1A; CKMT1B | NTRK1 3801/4885LTK 4647/4885TYRO3 3352/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.