SCHEMBL844706

SCHEMBL844706

Cn1c2ccsc2c2sccc21

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NTRK1 P04629 1/20 0.43
LTK P29376 1/20 0.43
TYRO3 Q06418 1/20 0.43
NTRK2 Q16620 1/20 0.43
CLK4 Q9HAZ1 1/20 0.43
EGLN1 Q9GZT9 1/20 0.38
GAA P10253 1/20 0.37
GPR3 P46089 1/20 0.36
PKM P14618 3/20 0.35
PKLR P30613 3/20 0.35
KDM1A O60341 5/20 0.32
KMT2A Q03164 2/20 0.32
MEN1 O00255 1/20 0.32
NPC1 O15118 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
MAPT P10636 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL818831 0.80 GPR3 (0.58) GAAGPR3PKMPKLRKMT2A
SCHEMBL21610564 0.78 PKM (0.35) NTRK1LTKTYRO3NTRK2CLK4
SCHEMBL17344224 0.77 GAA (0.35) NTRK1LTKTYRO3NTRK2CLK4
SCHEMBL13451226 0.76 LMNA (0.33) NTRK1LTKTYRO3NTRK2CLK4
SCHEMBL17236311 0.76 PKM (0.33) NTRK1LTKTYRO3NTRK2CLK4
SCHEMBL18689573 0.73 GRIK1 (0.48) EGLN1GAAPKMKMT2AMEN1
SCHEMBL1271477 0.73 EGLN1 (0.37) NTRK1LTKTYRO3NTRK2CLK4
SCHEMBL23312221 0.72 ALDH1A1 (0.39) NTRK1LTKTYRO3NTRK2CLK4
SCHEMBL23868782 0.72 EGLN1 (0.39) EGLN1GAAPKMPKLRKMT2A
SCHEMBL24397498 0.72 KMT2A (0.40) NTRK1LTKTYRO3NTRK2CLK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230227475-A1 Asymmetric Fused Aromatic Ring Derivative Containing Sulfonyl Group, Use Thereof, Hydrogen Production Device and Optoelectronic Component NATIONAL TSING HUA UNIVERSITY (TW) 2023-07-20 US disclosed
US-11365203-B2 Fluorescent dye and preparation method and use thereof FLUORESCENCE DIAGNOSIS (SHANGHAI) BIOTECH COMPANY LTD. (CN) 2022-06-21 US disclosed
US-20190241584-A1 FLUORESCENT DYE AND PREPARATION METHOD AND USE THEREOF EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2019-08-08 US disclosed
US-9917260-B2 Compounds with terminal heteroarylcyanovinylene groups and their use in organic solar cells BASF SE (DE) 2018-03-13 US disclosed
US-9705090-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-07-11 US disclosed
US-9705090-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-07-11 US disclosed
US-9634259-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-04-25 US disclosed
US-9634259-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-04-25 US disclosed
US-20170092435-A1 PHOTOELECTRIC CONVERSION ELEMENT, DYE-SENSITIZED SOLAR CELL, METAL COMPLEX DYE, DYE SOLUTION, AND TERPYRIDINE COMPOUND OR ESTERIFIED PRODUCT THEREOF FUJIFILM CORPORATION (JP) 2017-03-30 US disclosed
US-20170092435-A1 PHOTOELECTRIC CONVERSION ELEMENT, DYE-SENSITIZED SOLAR CELL, METAL COMPLEX DYE, DYE SOLUTION, AND TERPYRIDINE COMPOUND OR ESTERIFIED PRODUCT THEREOF FUJIFILM CORPORATION (JP) 2017-03-30 US disclosed
US-8859718-B2 Synthesis of conjugated polymers via oxidative polymerization and related compositions SOLVAY USA, INC. (US) 2014-10-14 US disclosed
US-20130109813-A1 SYNTHESIS OF CONJUGATED POLYMERS VIA OXIDATIVE POLYMERIZATION AND RELATED COMPOSITIONS PLEXTRONICS, INC. (US) 2013-05-02 US disclosed
US-20120264649-A1 AGENTS FOR ENHANCED CHARGE TRANSPORT ACROSS MICROBIAL MEMBRANES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2012-10-18 US disclosed
US-8143399-B2 Photosensitizer dye NATIONAL CENTRAL UNIVERSITY (TW) 2012-03-27 US disclosed
US-7645879-B2 Photosensitizer dye NATIONAL CENTRAL UNIVERSITY (TW) 2010-01-12 US disclosed
US-20090209761-A1 PHOTOSENSITIZER DYE NATIONAL CENTRAL UNIVERSITY (TW) 2009-08-20 US disclosed
US-20090209762-A1 PHOTOSENSITIZER DYE NATIONAL CENTRAL UNIVERSITY (TW) 2009-08-20 US disclosed
EP-1956011-A1 AMINE COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT EMPLOYING THE SAME Idemitsu Kosan Co., Ltd. (JP) 2008-08-13 EP disclosed
US-20070132372-A1 AMINE BASED COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2007-06-14 US disclosed
US-20070132372-A1 AMINE BASED COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2007-06-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070132372-A1 AMINE BASED COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME KCNH2, SLC7A5, KCNH3 NTRK1 350/4885LTK 2087/4885TYRO3 2903/4885
US-20230227475-A1 Asymmetric Fused Aromatic Ring Derivative Containing Sulfonyl Group, Use Thereof, Hydrogen Production Device and Optoelectronic Component AHR, STS, HAT1 NTRK1 3166/4885LTK 2542/4885TYRO3 433/4885
US-20090209762-A1 PHOTOSENSITIZER DYE CRY2, CRY1, PPOX NTRK1 4884/4885LTK 4352/4885TYRO3 3155/4885
US-20170092435-A1 PHOTOELECTRIC CONVERSION ELEMENT, DYE-SENSITIZED SOLAR CELL, METAL COMPLEX DYE, DYE SOLUTION, AND TERPYRIDINE COMPOUND OR ESTERIFIED PRODUCT THEREOF CRY2, CACNA1S, CACNA1E NTRK1 4173/4885LTK 419/4885TYRO3 3703/4885
US-20190241584-A1 FLUORESCENT DYE AND PREPARATION METHOD AND USE THEREOF DNASE1, POLRMT, DCLRE1B NTRK1 3230/4885LTK 3571/4885TYRO3 4100/4885
US-20090209761-A1 PHOTOSENSITIZER DYE CRY1, CRY2, TYR NTRK1 4884/4885LTK 4585/4885TYRO3 3192/4885
US-11365203-B2 Fluorescent dye and preparation method and use thereof DNASE1, POLRMT, DCLRE1B NTRK1 3230/4885LTK 3571/4885TYRO3 4100/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.