SCHEMBL504179

SCHEMBL504179

CC(Cl)C1(N(N=O)C(N)=O)CCCCC1

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6313653 0.76
SCHEMBL4017065 0.73 ALDH1A1 (0.38) ALDH1A1SMN1; SMN2
SCHEMBL87566 0.60
SCHEMBL29026457 0.58
SCHEMBL29000323 0.58 CYP2C19 (0.35)
SCHEMBL1651627 0.56
SCHEMBL572320 0.56 ALDH1A1 (0.34) ALDH1A1SMN1; SMN2
SCHEMBL19439409 0.55 SLC6A4 (0.30)
SCHEMBL18052040 0.55 EPHX1 (0.33) ALDH1A1SMN1; SMN2
SCHEMBL8958407 0.55 ALDH1A1 (0.33) ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114558032-A Method for preparing platelets from pluripotent stem cells and composition thereof 安斯泰来再生医药协会 2022-05-31 CN disclosed
CN-105101979-B Method for preparing platelets from pluripotent stem cells and composition thereof 安斯泰来再生医药协会 2021-10-08 CN disclosed
EP-3191114-B1 OCCIDIOFUNGIN FORMULATIONS AND USES THEREOF UNIV MISSISSIPPI STATE (US) 2021-03-03 EP disclosed
US-10265374-B2 Occidiofungin formations and uses thereof MISSISSIPPI STATE UNIVERSITY (US) 2019-04-23 US disclosed
US-20170281721-A1 OCCIDIOFUNGIN FORMATIONS AND USES THEREOF MISSISSIPPI STATE UNIVERSITY (US) 2017-10-05 US disclosed
EP-3191114-A1 OCCIDIOFUNGIN FORMULATIONS AND USES THEREOF Smith, James (US) 2017-07-19 EP disclosed
WO-2016040940-A1 OCCIDIOFUNGIN FORMULATIONS AND USES THEREOF AUSTIN, FRANK (US) 2016-03-17 WO disclosed
US-8476246-B2 Combination of a chemotherapeutic agent and an inhibitor of the TGF-beta system ANTISENSE PHARMA GMBH (DE) 2013-07-02 US disclosed
US-20120027873-A1 COMBINATION OF A CHEMOTHERAPEUTIC AGENT AND AN INHIBITOR OF THE TGF-BETA SYSTEM ANTISENSE PHARMA GMBH (DE) 2012-02-02 US disclosed
EP-2340308-A1 COMBINATION OF A CHEMOTHERAPEUTIC AGENT AND AN INHIBITOR OF THE TGF-BETA SYSTEM Antisense Pharma GmbH (DE) 2011-07-06 EP disclosed
US-20070196269-A1 Pharmaceutical composition ANTISENSE PHARMA GMBH (DE) 2007-08-23 US disclosed
EP-1694840-A2 COMBINATION THERAPY ASSOCIATING A TGF-BETA ANTAGONIST WITH A CHEMOTHERAPEUTIC AGENT Antisense Pharma GmbH (DE) 2006-08-30 EP disclosed
US-6949350-B1 Chemosensitivity determination using phosphatidylserine EVOTEC ANALYTICAL SYSTEMS GMBH (DE) 2005-09-27 US disclosed
US-20050203082-A1 Combination therapy with inhibitors of inducible nitric oxide synthase and alkylating agents PHARMACIA CORPORATION 2005-09-15 US disclosed
WO-2005059133-A2 COMBINATION THERAPY ASSOCIATING A TGF-BRETA ANTAGONIST WITH A CHEMIOTHERAPEUTIC AGENT ANTISENSE PHARMA GMBH (DE) 2005-06-30 WO disclosed
WO-2005025620-A2 COMBINATION THERAPY WITH INHIBITORS OF INDUCIBLE NITRIC OXIDE SYNTHASE AND ALKYLATING AGENTS PHARMACIA CORPORATION (US) 2005-03-24 WO disclosed
EP-0525188-B1 LIPOSOME COMPOSITION TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1995-03-01 EP disclosed
US-5252336-A Good dispersibility; high stability; high encapsulation properties TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1993-10-12 US disclosed
EP-0525188-A1 LIPOSOME COMPOSITION. TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1993-02-03 EP disclosed
WO-1991016040-A1 LIPOSOME COMPOSITION TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1991-10-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050203082-A1 Combination therapy with inhibitors of inducible nitric oxide synthase and alkylating agents NOS2, NOS1, NOS3 ALDH1A1 995/4885SMN1; SMN2 3595/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.