SCHEMBL4017065

SCHEMBL4017065

CC1(N(N=O)C(N)=O)CCCCC1

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.38
SMN1; SMN2 Q16637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL504179 0.73 ALDH1A1 (0.30) ALDH1A1SMN1; SMN2
SCHEMBL6313653 0.70
SCHEMBL28807495 0.65 ALDH1A1 (0.33) ALDH1A1SMN1; SMN2
SCHEMBL14974789 0.64 ALDH1A1 (0.33) ALDH1A1SMN1; SMN2
Urea SCHEMBL1840880 0.63 ALDH1A1 (0.43) ALDH1A1SMN1; SMN2
SCHEMBL24272639 0.63 OPRM1 (0.38) ALDH1A1SMN1; SMN2
SCHEMBL9400068 0.63 ALDH1A1 (0.35) ALDH1A1SMN1; SMN2
SCHEMBL14501954 0.63 OPRM1 (0.38) ALDH1A1SMN1; SMN2
SCHEMBL23982634 0.62 HDAC1 (0.30)
SCHEMBL516698 0.61 ALDH1A1 (0.52) ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0668782-B1 COMBINATION OF ANTINEOPLASTIC AGENT AND ANTISENSE OLIGONUCLEOTIDES FOR TREATMENT OF CANCER UNIV TEMPLE (US) 2001-04-11 EP claimed
EP-0668782-A1 COMBINATION OF ANTINEOPLASTIC AGENT AND ANTISENSE OLIGONUCLEOTIDES FOR TREATMENT OF CANCER TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 1995-08-30 EP claimed
WO-1994008625-A1 COMBINATION OF ANTINEOPLASTIC AGENT AND ANTISENSE OLIGONUCLEOTIDES FOR TREATMENT OF CANCER TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 1994-04-28 WO claimed
US-12605332-B2 Transdermal delivery formulations ALBERT EINSTEIN COLLEGE OF MEDICINE (US) 2026-04-21 US disclosed
US-12478576-B2 Transdermal delivery formulations ALBERT EINSTEIN COLLEGE OF MEDICINE (US) 2025-11-25 US disclosed
EP-4591711-A1 COMPOSITIONS FOR BLOOD STORAGE AND TRANSFUSIONS Albert Einstein College of Medicine (US) 2025-07-30 EP disclosed
CN-120153255-A Methods of predicting response to cancer treatment 佩普托米克公司 2025-06-13 CN disclosed
EP-4545068-A1 TRANSDERMAL DELIVERY FORMULATIONS Albert Einstein College of Medicine (US) 2025-04-30 EP disclosed
CN-119868249-A Transdermal delivery formulation 阿尔伯特爱因斯坦医学院 2025-04-25 CN disclosed
US-20250064721-A1 TRANSDERMAL DELIVERY FORMULATIONS ALBERT EINSTEIN COLLEGE OF MEDICINE 2025-02-27 US disclosed
US-20240390264-A1 TRANSDERMAL DELIVERY FORMULATIONS ALBERT EINSTEIN COLLEGE OF MEDICINE 2024-11-28 US disclosed
CN-111132967-A Cyclic olefin substituted heteroaromatic ring compound and application thereof 和记黄埔医药(上海)有限公司 2020-05-08 CN disclosed
CN-105793422-B Antisense-induced exon 2 inclusion in acid α -glucosidase 萨罗塔治疗公司(美国) 2020-03-03 CN disclosed
CN-103826456-B GLI albumen in human cancer is targetted by small molecule 加利福尼亚大学董事会 2017-09-19 CN disclosed
US-20170211073-A1 ANTISENSE ANTINEOPLASTIC AGENT Nakano, Kenji (JP) 2017-07-27 US disclosed
EP-3168305-A1 ANTISENSE ANTINEOPLASTIC AGENT Nakano, Kenji (JP) 2017-05-17 EP disclosed
WO-2009085216-A2 COMPOSITIONS AND METHODS FOR DETECTING OR ELIMNINATING SENESCENT CELLS TO DIAGNOSE OR TREAT DISEASE SQUICOR (US) 2009-07-09 WO disclosed
EP-1960551-A2 METHODS AND DEVICES FOR IDENTIFYING BIOMARKERS OF TREATMENT RESPONSE AND USE THEREOF TO PREDICT TREATMENT EFFICACY Medical Prognosis Institute (DK) 2008-08-27 EP disclosed
WO-2007072225-A2 METHODS AND DEVICES FOR IDENTIFYING BIOMARKERS OF TREATMENT RESPONSE AND USE THEREOF TO PREDICT TREATMENT EFFICACY MEDICAL PROGNOSIS INSTITUTE (DK) 2007-06-28 WO disclosed
EP-0668782-B1 COMBINATION OF ANTINEOPLASTIC AGENT AND ANTISENSE OLIGONUCLEOTIDES FOR TREATMENT OF CANCER UNIV TEMPLE (US) 2001-04-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12605332-B2 Transdermal delivery formulations NOS1, NOS2, VDR ALDH1A1 1757/4885SMN1; SMN2 2480/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.