SCHEMBL504244

SCHEMBL504244

Cc1ccc(S(=O)(=O)O)cc1.O=C(c1ccccc1)C(O)(CO)c1ccccc1

nearest known ligand 0.47

Known targets — ChEMBL curated mechanism

ABL1BMXBRAFBTKCHRNA4CHRNB2CSNK1EEGFRERBB2F10FLT1FLT3FLT4IGF1RINSRITKJAK3KDRKITOPRM1PARP1PARP2PDGFRBPIK3CDRAF1RETSLC18A2TECTXKdacAdacBdacCftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RECQL P46063 1/20 0.47
ALDH1A1 P00352 7/20 0.44
TDP1 Q9NUW8 2/20 0.44
TP53 P04637 1/20 0.44
CYP2D6 P10635 2/20 0.41
MAPK1 P28482 1/20 0.41
HSD11B1 P28845 1/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
NPSR1 Q6W5P4 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
TSHR P16473 2/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
GAA P10253 2/20 0.39
PKM P14618 1/20 0.39
LMNA P02545 3/20 0.39
L3MBTL1 Q9Y468 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27612829 0.90 SMN1; SMN2 (0.50) RECQLALDH1A1CYP2D6HSD11B1SMN1; SMN2
SCHEMBL11057570 0.84 CES1 (0.45) ALDH1A1TDP1CYP2D6MAPK1HSD11B1
SCHEMBL499362 0.83 RECQL (0.46) RECQLALDH1A1TDP1TP53CYP2D6
SCHEMBL27575142 0.81 RECQL (0.56) RECQLALDH1A1TDP1TP53CYP2D6
SCHEMBL36374 0.81 CES1 (0.48) RECQLALDH1A1TDP1MAPK1MEN1
Trifluoromethanesulfonic Acid SCHEMBL503620 0.79 CES1 (0.46) CYP2D6MAPK1HSD11B1NPC1RAB9A
Methoxymethane SCHEMBL36098 0.78 CES1 (0.56) ALDH1A1TDP1MAPK1MEN1KMT2A
SCHEMBL547325 0.77 RECQL (0.46) RECQLALDH1A1TDP1TP53CYP2D6
SCHEMBL11181163 0.77 RECQL (0.43) RECQLALDH1A1TDP1TP53CYP2D6
SCHEMBL9575058 0.77 ALDH1A1 (0.42) RECQLALDH1A1TDP1TP53HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 267 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5994022-A BECOMES SOLUBLE IN ALKALI DEVELOPING SOLUTION BY ACTION OF AN ACID JSR CORPORATION (JP) 1999-11-30 US claimed
CN-122043858-A EUV patterned resist formation method 亚历克斯·P·G·罗宾逊 2026-05-15 CN disclosed
WO-2024075641-A1 POLYMER MATERIAL FOR USE IN DENTISTRY サンメディカル株式会社 2024-04-11 WO disclosed
WO-2023243636-A1 MEMBER PROCESSING METHOD 日東電工株式会社 2023-12-21 WO disclosed
WO-2023243634-A1 TRANSFER SHEET 日東電工株式会社 2023-12-21 WO disclosed
WO-2023191112-A1 DENTAL CURABLE COMPOSITION HAVING FAVORABLE COLOR COMPATIBILITY クラレノリタケデンタル株式会社 2023-10-05 WO disclosed
US-11681227-B2 Enhanced EUV photoresist materials, formulations and processes IRRESISTIBLE MATERIALS LTD (GB) 2023-06-20 US disclosed
CN-113994256-A Method for forming EUV patterned resist 亚历克斯·P·G·罗宾逊 2022-01-28 CN disclosed
US-20200272050-A1 Enhanced EUV Photoresist Materials, Formulations and Processes IRRESISTIBLE MATERIALS, LTD (GB) 2020-08-27 US disclosed
CN-110998437-A Multi-trigger photoresist compositions and methods A·P·G·罗宾森 2020-04-10 CN disclosed
EP-0917000-A2 Positive resist composition and method for forming a resist pattern SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-05-19 EP disclosed
US-5891601-A DIPYRIDYL COMPOUND SUMITOMO CHEMICAL COMPANY, LTD. (JP) 1999-04-06 US disclosed
EP-0901043-A1 Radiation-sensitive resin composition JSR Corporation (JP) 1999-03-10 EP disclosed
EP-0898201-A1 Radiation sensitive resin composition JSR Corporation (JP) 1999-02-24 EP disclosed
EP-0843220-A1 Radiation sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1998-05-20 EP disclosed
US-5744511-A BLEND OF COUMARIN DYES, ACID GENERATOR AND ARYL BORATE TOKUYAMA CORPORATION (JP) 1998-04-28 US disclosed
EP-0837367-A2 Positive resist composition comprising a dipyridyl compound SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1998-04-22 EP disclosed
EP-0837368-A1 Positive resist composition SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1998-04-22 EP disclosed
EP-0793144-A2 Radiation sensitive composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1997-09-03 EP disclosed
EP-0738928-A2 Visible-ray polymerization initiator and visible-ray polymerizable composition TOKUYAMA CORPORATION (JP) 1996-10-23 EP disclosed