Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.48 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.48 |
| ▸ | CETP | P11597 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | THRA | P10827 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | MLYCD | O95822 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5044086 | 0.89 | SPHK2 (0.57) | NAAASIGMAR1TMEM97HDAC3MEN1 | |
| SCHEMBL1239602 | 0.87 | NAAA (0.50) | NAAASIGMAR1TMEM97CETPHDAC3 | |
| SCHEMBL1853317 | 0.87 | NAAA (0.66) | NAAASIGMAR1TMEM97HDAC3L3MBTL1 | |
| SCHEMBL5044268 | 0.85 | NAAA (0.60) | NAAASIGMAR1TMEM97HDAC3MEN1 | |
| SCHEMBL5048883 | 0.81 | HDAC3 (0.60) | NAAASIGMAR1TMEM97HDAC3MEN1 | |
| SCHEMBL5045478 | 0.81 | NAAA (0.54) | NAAASIGMAR1TMEM97CETPMEN1 | |
| SCHEMBL1859810 | 0.81 | NAAA (0.56) | NAAASIGMAR1TMEM97HDAC3MEN1 | |
| SCHEMBL1854504 | 0.80 | SIGMAR1 (0.49) | NAAASIGMAR1TMEM97CETPMEN1 | |
| SCHEMBL27571120 | 0.80 | NAAA (0.72) | NAAAHDAC3MEN1KMT2AL3MBTL1 | |
| SCHEMBL1239475 | 0.80 | NAAA (0.53) | NAAASIGMAR1TMEM97HDAC3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732534-B1 | USE OF METHYLENE AMIDE DERIVATIVES IN CARDIOVASCULAR DISORDERS | SERONO LAB (CH) | 2008-07-23 | — | — | EP | claimed |