Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.45 |
| ▸ | PPARA | Q07869 | 4/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 9/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | EYA3 | Q99504 | 1/20 | 0.40 |
| ▸ | LSS | P48449 | 1/20 | 0.40 |
| ▸ | MTTP | P55157 | 2/20 | 0.39 |
| ▸ | PPARD | Q03181 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5044450 | 0.87 | MAPK14 (0.47) | PPARGEPHX2PPARAPTPN1MAPK14 | |
| SCHEMBL1851704 | 0.82 | LSS (0.46) | PPARGEPHX2PPARAPTPN1MAPK14 | |
| SCHEMBL1854032 | 0.81 | LSS (0.41) | PPARGEPHX2PPARAPTPN1MAPK14 | |
| SCHEMBL1855758 | 0.80 | LSS (0.44) | PPARGEPHX2PTPN1MAPK14EYA3 | |
| SCHEMBL6022117 | 0.77 | PTPN1 (0.51) | PTPN1EYA3 | |
| SCHEMBL5048860 | 0.73 | MLYCD (0.53) | PPARGEPHX2PPARAPPARD | |
| SCHEMBL1860426 | 0.72 | HDAC3 (0.50) | PTPN1EYA3 | |
| SCHEMBL6022101 | 0.71 | PPARG (0.46) | PPARGEPHX2PPARAMAPK14LSS | |
| SCHEMBL6716858 | 0.70 | MLYCD (0.54) | PPARGPPARAPPARD | |
| SCHEMBL5045562 | 0.68 | ALDH1A1 (0.47) | PPARGEPHX2PPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732534-B1 | USE OF METHYLENE AMIDE DERIVATIVES IN CARDIOVASCULAR DISORDERS | SERONO LAB (CH) | 2008-07-23 | — | — | EP | claimed |