Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14935873 | 1.00 | ALDH1A1 (0.36) | ALDH1A1MAPTPTGS1KDM4EMAPK1 | |
| SCHEMBL21403573 | 0.78 | ALDH1A1 (0.43) | ALDH1A1MAPTPTGS1KDM4ETHRB | |
| SCHEMBL8769242 | 0.76 | ALDH1A1 (0.41) | ALDH1A1MAPTPTGS1 | |
| N-Acetyl Penicillamine SCHEMBL4468919 | 0.74 | MAPT (0.43) | ALDH1A1MAPTPTGS1KDM4ETHRB | |
| N-Acetyl Penicillamine SCHEMBL34351 | 0.74 | MAPT (0.43) | ALDH1A1MAPTPTGS1KDM4ETHRB | |
| N-Acetyl Penicillamine SCHEMBL521764 | 0.74 | MAPT (0.43) | ALDH1A1MAPTPTGS1KDM4ETHRB | |
| SCHEMBL30317213 | 0.71 | ALDH1A1 (0.44) | ALDH1A1MAPTPTGS1 | |
| SCHEMBL31668698 | 0.71 | ALDH1A1 (0.44) | ALDH1A1MAPTPTGS1 | |
| SCHEMBL3109035 | 0.70 | ALDH1A1 (0.36) | ALDH1A1MAPTPTGS1FOLH1 | |
| SCHEMBL31196416 | 0.70 | ALOX15 (0.38) | ALDH1A1MAPTPTGS1MAPK1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120027720-A1 | PEPTIDE CONJUGATES | ALBA THERAPEUTICS CORPORATION | 2012-02-02 | — | — | US | disclosed |
| EP-1917020-A1 | MONOMETHYLVALINE COMPOUNDS HAVING PHENYLALANINE SIDE-CHAIN MODIFICATIONS AT THE C-TERMINUS | Seattle Genetics, Inc. (US) | 2008-05-07 | — | — | EP | disclosed |
| WO-2007008603-A1 | MONOMETHYLVALINE COMPOUNDS HAVING PHENYLALANINE SIDE-CHAIN MODIFICATIONS AT THE C-TERMINUS | SEATTLE GENETICS, INC. (US) | 2007-01-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120027720-A1 | PEPTIDE CONJUGATES | VIP, IAPP, NGLY1 | ALDH1A1 3745/4885MAPT 1581/4885PTGS1 4292/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.