Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.33 |
| ▸ | APP | P05067 | 2/20 | 0.33 |
| ▸ | ANPEP | P15144 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.31 |
| ▸ | FABP2 | P12104 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5047725 | 0.84 | LMNA (0.33) | ALDH1A1GAAMEN1KMT2ATSHR | |
| Hydrochloric Acid SCHEMBL5040718 | 0.73 | F2 (0.43) | — | |
| SCHEMBL5037863 | 0.72 | PTGS2 (0.42) | ALDH1A1GAACYP2C19PTGS2APP | |
| SCHEMBL2352769 | 0.72 | ALDH1A1 (0.49) | ALDH1A1GAAL3MBTL1KDM4EAKR1C2 | |
| SCHEMBL2345247 | 0.68 | PTGS2 (0.45) | ALDH1A1PTGS2AKR1C2AKR1C3PTGS1 | |
| SCHEMBL5045404 | 0.65 | CDC7 (0.41) | ALDH1A1MAPTHPGD | |
| SCHEMBL31147960 | 0.65 | AKR1C3 (0.43) | ALDH1A1GAAL3MBTL1KDM4ECYP2C19 | |
| SCHEMBL31147959 | 0.65 | AKR1C3 (0.43) | ALDH1A1GAAL3MBTL1KDM4ECYP2C19 | |
| SCHEMBL5040984 | 0.64 | MIF (0.39) | ALDH1A1GAAL3MBTL1KDM4ECYP2C19 | |
| SCHEMBL5042415 | 0.64 | ALDH1A1 (0.44) | ALDH1A1GAAL3MBTL1KDM4EAKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567498-B1 | MANDELIC ACID DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2008-01-23 | — | — | EP | disclosed |
| US-7129238-B2 | Mandelic acid derivatives | HOFFMANN-LA ROCHE INC. (US) | 2006-10-31 | — | — | US | disclosed |
| US-20040122057-A1 | Novel mandelic acid derivatives | HOFFMANN-LA ROCHE INC. | 2004-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040122057-A1 | Novel mandelic acid derivatives | F7, F11, F9 | ALDH1A1 519/4885GAA 1312/4885L3MBTL1 1475/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.