Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.57 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PLK1 | P53350 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34465762 | 0.83 | CHRNB2 (0.43) | TAAR1CHRNB2CHRNA4KDM4EGAA | |
| SCHEMBL25804595 | 0.82 | GAA (0.49) | KDM4EGAAMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL8372045 | 0.80 | KDM4E (0.51) | CHRNB2CHRNA4KDM4EGAAMAPT | |
| SCHEMBL13232446 | 0.80 | PLK1 (0.47) | KDM4EGAAMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL29609117 | 0.80 | KDM4E (0.59) | CHRNB2CHRNA4KDM4EGAAMAPT | |
| SCHEMBL2125695 | 0.80 | KDM4E (0.59) | CHRNB2CHRNA4KDM4EGAAMAPT | |
| SCHEMBL12140714 | 0.78 | GAA (0.58) | TAAR1KDM4EGAAMAPTTMEM97 | |
| Hydrochloric Acid SCHEMBL5128680 | 0.78 | KDM4E (0.58) | CHRNB2CHRNA4KDM4EGAAMAPT | |
| SCHEMBL6788044 | 0.78 | ALDH1A1 (0.49) | KDM4EGAAMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL255686 | 0.78 | KDM4E (0.56) | KDM4EMAPTATMALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2481731-B1 | Insecticidal (1,3,5)-triazinyl phenyl hydrazones | DOW AGROSCIENCES LLC (US) | 2013-10-23 | — | — | EP | disclosed |
| EP-2197857-B1 | INSECTICIDAL (1,3,5)-TRIAZINYL PHENYL HYDRAZONES | DOW AGROSCIENCES LLC (US) | 2013-03-06 | — | — | EP | disclosed |
| EP-2481731-A1 | Insecticidal (1,3,5)-triazinyl phenyl hydrazones | Dow AgroSciences LLC (US) | 2012-08-01 | — | — | EP | disclosed |
| EP-2481730-A1 | Insecticidal (1,3,5)-triazinyl phenyl hydrazones | Dow AgroSciences LLC (US) | 2012-08-01 | — | — | EP | disclosed |
| US-8188273-B2 | Insecticidal (1,3,5)-triazinyl phenyl hydrazones | DOW AGROSCIENCES, LLC. (US) | 2012-05-29 | — | — | US | disclosed |
| US-20120040837-A1 | INSECTICIDAL (1,3,5)-TRIAZINYL PHENYL HYDRAZONES | DOW AGROSCIENCES LLC (US) | 2012-02-16 | — | — | US | disclosed |
| US-8067588-B2 | Insecticidal (1,3,5)-triazinyl phenyl hydrazones | DOW AGROSCIENCES LLC (US) | 2011-11-29 | — | — | US | disclosed |
| WO-2009048750-A2 | INSECTICIDAL (1,3,5)-TRIAZINYL PHENYL HYDRAZONES | DOW AGROSCIENCES LLC (US) | 2009-04-16 | — | — | WO | disclosed |
| US-20090093481-A1 | INSECTICIDAL (1,3,5)-TRIAZINYL PHENYL HYDRAZONES | DOW AGROSCIENCES LLC (US) | 2009-04-09 | — | — | US | disclosed |
| US-7345038-B2 | Pyridyloxymethyl and benzisoxazole azabicyclic derivatives | PFIZER, INC (US) | 2008-03-18 | — | — | US | disclosed |
| EP-1608648-A1 | PYRIDYLOXYMETHYL AND BENZISOXAZOLE AZABICYCLIC DERIVATIVES | Pfizer Products Inc. (US) | 2005-12-28 | — | — | EP | disclosed |
| US-20050026922-A1 | For treating CNS or other disorders, including concurrent treatment of disorders such as schizophrenia and depression; side effect reduction; for example, (7R,9aS)-trans-7-[6-(2,6-Dimethyl-piperidin-1-ylmethyl)-pyridin-2-yloxymethyl]-2-(5-fluoro-benzo[d]isoxazol-3-yl)-octahydro-pyrido[1,2-a]pyrazine | PFIZER INC | 2005-02-03 | — | — | US | disclosed |
| WO-2004081007-A1 | PYRIDYLOXYMETHYL AND BENZISOXAZOLE AZABICYCLIC DERIVATIVES | PFIZER PRODUCTS INC. (US) | 2004-09-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090093481-A1 | INSECTICIDAL (1,3,5)-TRIAZINYL PHENYL HYDRAZONES | HELZ, API5, CRYZ | TAAR1 2144/4885CHRNB2 2344/4885CHRNA4 1752/4885 |
| US-20120040837-A1 | INSECTICIDAL (1,3,5)-TRIAZINYL PHENYL HYDRAZONES | HELZ, API5, CRYZ | TAAR1 2144/4885CHRNB2 2344/4885CHRNA4 1752/4885 |
| US-20050026922-A1 | For treating CNS or other disorders, including concurrent treatment of disorders such as schizophrenia and depression; side effect reduction; for example, (7R,9aS)-trans-7-[6-(2,6-Dimethyl-piperidin-1-ylmethyl)-pyridin-2-yloxymethyl]-2-(5-fluoro-benzo[d]isoxazol-3-yl)-octahydro-pyrido[1,2-a]pyrazine | GRM7, GRIN2C, HTR7 | TAAR1 230/4885CHRNB2 116/4885CHRNA4 59/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.