Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 5/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7525635 | 0.78 | MAOB (0.43) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL854325 | 0.76 | APP (0.41) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL5601610 | 0.65 | TSHR (0.40) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL703 | 0.61 | LMNA (0.64) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL22369114 | 0.61 | L3MBTL1 (0.43) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL3487763 | 0.61 | L3MBTL1 (0.43) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL5690860 | 0.61 | MAPT (0.47) | L3MBTL1MAPTSMN1; SMN2MAPK1TDP1 | |
| SCHEMBL547985 | 0.60 | HTR1A (0.67) | LMNAL3MBTL1MAPTMAPK1TDP1 | |
| SCHEMBL7451939 | 0.60 | MEN1 (0.58) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL3275212 | 0.60 | ALOX5 (0.53) | LMNACYP1A2PTGS1SLC6A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008014240-A2 | DIMERIC IAP INHIBITORS | TETRALOGIC PHARMACEUTICALS CORPORATION (US) | 2008-01-31 | — | — | WO | disclosed |