Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.67 |
| ▸ | DRD2 | P14416 | 3/20 | 0.67 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | LIPE | Q05469 | 1/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.49 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetonitrile SCHEMBL27809938 | 0.90 | HTR1A (0.56) | HTR1ADRD2ABCB1GAAMAPT | |
| SCHEMBL8707848 | 0.90 | HTR1A (0.56) | HTR1ADRD2ABCB1GAAMAPT | |
| SCHEMBL32670477 | 0.87 | ALDH1A1 (0.62) | HTR1ADRD2ABCB1MAPTMAPK1 | |
| SCHEMBL3243180 | 0.85 | HTR1A (0.54) | HTR1ADRD2ABCB1GAAMAPT | |
| SCHEMBL7450789 | 0.84 | MAPT (0.71) | HTR1ADRD2ABCB1GAAMAPT | |
| SCHEMBL3996790 | 0.84 | DRD2 (0.57) | HTR1ADRD2ABCB1GAAMAPT | |
| SCHEMBL29087574 | 0.84 | RXRA (0.68) | MAPTKDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL9277698 | 0.83 | HTR1A (0.71) | HTR1ADRD2ABCB1GAAMAPT | |
| SCHEMBL2394736 | 0.83 | L3MBTL1 (0.48) | HTR1ADRD2MAPTTDP1L3MBTL1 | |
| SCHEMBL7450663 | 0.83 | HTR1A (0.51) | HTR1ADRD2ABCB1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101279899-B | Preparation of phenol 2-[2-(3-methoxyphenyl) ethyl] | UNIV CHINA PHARMA | 2010-06-02 | — | — | CN | claimed |
| CN-101279899-A | Preparation of phenol 2-[2-(3-methoxyphenyl) ethyl] | UNIV CHINA PHARMA (CN) | 2008-10-08 | — | — | CN | claimed |
| EP-0873293-B1 | IMPROVED PROCESS FOR THE PREPARATION OF ALKYL OR ARYL ALDEHYDE INTERMEDIATES | ABBOTT LAB (US) | 2001-07-25 | — | — | EP | claimed |
| EP-0873293-A1 | IMPROVED PROCESS FOR THE PREPARATION OF ALKYL OR ARYL ALDEHYDE INTERMEDIATES | Abbott Laboratories (US) | 1998-10-28 | — | — | EP | claimed |
| WO-1997023439-A1 | IMPROVED PROCESS FOR THE PREPARATION OF ALKYL OR ARYL ALDEHYDE INTERMEDIATES | ABBOTT LABORATORIES (US) | 1997-07-03 | — | — | WO | claimed |
| EP-3782996-B1 | NRF2 REGULATORS | GLAXOSMITHKLINE IP DEV LTD (GB) | 2024-04-10 | — | — | EP | disclosed |
| US-20230047296-A1 | Nrf2 REGULATORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2023-02-16 | — | — | US | disclosed |
| EP-3796906-A1 | INDANES AS NRF2 ACTIVATORS | GlaxoSmithKline Intellectual Property Management Limited (GB) | 2021-03-31 | — | — | EP | disclosed |
| CN-108112251-B | NRF2 modulators | 葛兰素史克知识产权发展有限公司 | 2021-03-05 | — | — | CN | disclosed |
| EP-3782996-A1 | NRF2 REGULATORS | GlaxoSmithKline Intellectual Property Development Limited (GB) | 2021-02-24 | — | — | EP | disclosed |
| EP-3307739-B1 | NRF2 REGULATORS | GLAXOSMITHKLINE IP DEV LTD (GB) | 2020-10-07 | — | — | EP | disclosed |
| US-10604509-B2 | Nrf2 regulators | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2020-03-31 | — | — | US | disclosed |
| EP-0207605-B1 | HYPOGLYCEMIC THIAZOLIDINEDIONES | PFIZER INC. (US) | 1990-02-07 | — | — | EP | disclosed |
| US-4703052-A | Hypoglycemic thiazolidinediones | PFIZER INC. (US) | 1987-10-27 | — | — | US | disclosed |
| EP-0230893-A2 | Paramagnetic chelates | BRACCO INDUSTRIA CHIMICA Società per Azioni (IT) | 1987-08-05 | — | — | EP | disclosed |
| CN-86104075-A | Preparation method of hypoglycemic agent-thiazolidinedione | — | 1987-03-11 | — | — | CN | disclosed |
| EP-0207605-A1 | Hypoglycemic thiazolidinediones | PFIZER INC. (US) | 1987-01-07 | — | — | EP | disclosed |
| WO-1986007056-A1 | HYPOGLYCEMIC THIAZOLIDINEDIONES | PFIZER INC. (US) | 1986-12-04 | — | — | WO | disclosed |
| US-4012389-A | ANTICOAGULANTS | DONAU-PHARMAZIE GESELLSCHAFT M.B.H. (OE) | 1977-03-15 | — | — | US | disclosed |
| US-3935214-A | ANTICOAGULANT | DONAU-PHARMAZIE GESELLSCHAFT M.B.H. (OE) | 1976-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10604509-B2 | Nrf2 regulators | NFE2L2, KEAP1, NQO1 | HTR1A 2726/4885DRD2 3638/4885ABCB1 375/4885 |
| US-20230047296-A1 | Nrf2 REGULATORS | NFE2L2, KEAP1, NQO1 | HTR1A 2782/4885DRD2 3932/4885ABCB1 264/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.