Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 4/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.47 |
| ▸ | THRA | P10827 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.46 |
| ▸ | MLYCD | O95822 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5044501 | 0.88 | NAAA (0.55) | NAAAL3MBTL1HDAC3TMEM97SIGMAR1 | |
| SCHEMBL1853582 | 0.87 | NAAA (0.50) | NAAAL3MBTL1HDAC3TMEM97SIGMAR1 | |
| SCHEMBL5044217 | 0.82 | KMT2A (0.49) | NAAAL3MBTL1HDAC3TMEM97SIGMAR1 | |
| SCHEMBL1853317 | 0.80 | NAAA (0.66) | NAAAL3MBTL1HDAC3TMEM97SIGMAR1 | |
| SCHEMBL5045561 | 0.76 | NAAA (0.60) | NAAAL3MBTL1HDAC3TMEM97SIGMAR1 | |
| SCHEMBL5048321 | 0.76 | NAAA (0.53) | NAAAL3MBTL1TMEM97SIGMAR1HDAC1 | |
| SCHEMBL1857744 | 0.76 | NAAA (0.53) | NAAAL3MBTL1HDAC3TMEM97SIGMAR1 | |
| SCHEMBL5048883 | 0.74 | HDAC3 (0.60) | NAAAHDAC3TMEM97SIGMAR1HDAC1 | |
| SCHEMBL5044268 | 0.74 | NAAA (0.60) | NAAAL3MBTL1HDAC3TMEM97SIGMAR1 | |
| SCHEMBL5047915 | 0.73 | FOLH1 (0.55) | NAAAL3MBTL1HDAC3TMEM97SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732534-B1 | USE OF METHYLENE AMIDE DERIVATIVES IN CARDIOVASCULAR DISORDERS | SERONO LAB (CH) | 2008-07-23 | — | — | EP | claimed |